Method and apparatus for non-invasive monitoring of blood glucos

Details Method and apparatus for non-invasive monitoring of blood glucos Method and apparatus for non-invasive monitoring of blood glucos

1990-05-02

1992-06-09

Jaworski, Francis

Surgery

Truss

Pad

128632, A61B 800, A61B 500

Patent

active

051198193

ABSTRACT:
A new and improved method and apparatus are provided for non-invasive monitoring of changes in blood glucose concentration in a tissue specimen and particularly in an individual. The method uses acoustic velocity measurements for monitoring the effect of glucose concentration upon the density and adiabatic compressibility of the serum.
In a preferred embodiment, the acoustic velocity measurements are made through the earlobe of a subject by means of an acoustic probe or monitor which includes a transducer for transmitting and receiving ultrasonic energy pulses to and from the blood flowing in the subject's earlobe and a reflector for facilitating reflection of the acoustic pulses from the blood. The probe is designed in such a way that when properly affixed to an ear, the transducer is positioned flush against the anterior portion of an earlobe while the reflector is positioned flush against the interior portion of the earlobe. A microthermocouple is provided on the probe for monitoring the internal temperature of the blood being sampled.
An electrical system, essentially comprising a frequency generator, a time intervalometer and an oscilloscope, is linked to the glucose monitoring probe. The electrical system analyzes selected ones of the pulses reflected from the blood sample in order to determine therefrom the acoustic velocity of the blood which, in turn, provides a representation of the blood glucose concentration levels at the time of the acoustic velocity measurements.

REFERENCES:
patent: 4433690 (1984-02-01), Green et al.
patent: 4664124 (1987-05-01), Ingle et al.

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