Radiant energy – Invisible radiant energy responsive electric signalling – Infrared responsive
Patent
1994-02-14
1995-10-17
Dzierzynski, Paul M.
Radiant energy
Invisible radiant energy responsive electric signalling
Infrared responsive
2503418, 250343, 250347, 36441309, 364572, G01J 345, G01J 328
Patent
active
054593174
ABSTRACT:
Non-invasive measurements of physiological chemicals such as glucose are made using infrared radiation and a signal processing system that permits the construction of a device suited for home use. The level of a selected physiological chemical in a test subject is determined in a non-invasive and quantitative manner by a method comprising the steps of: (a) irradiating a portion of the test subject with near-infrared radiation such that the radiation is transmitted through or reflected from the test subject; (b) collecting data concerning the transmitted or reflected infrared radiation using a detector; (c) digitally filtering the collected data to isolate a portion of the data indicative of the physiological chemical; and (d) determining the amount of physiological chemical in the test subject by applying a defined mathematical model to the digitally filtered data. The data collected may be in the form of an absorbance spectrum, i.e., a representation of the variation in absorbance as a function of wavelength; or in the form of an interferogram, i.e., a representation of infrared light intensity as a function of the retardation of the moving mirror in the interferometer, and thus of time.
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Small et al., "Design of Optimized Finite Impulse Response Digital Filters for Use with Passive Fourier Transform Infrared Interferograms", Analytical Chemistry 62: 1768-1777 (1990).
Small et al.. "Effects of data Sampling Rate on Pattern recognition Analysis of FT-IR Interferograms", Applied Spectroscopy 46: 49-59 (1992).
Arnold Mark
Small Gary W.
Bruce David Vernon
Dzierzynski Paul M.
Ohio University
University of Iowa Res. Fdn.
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