Chemistry: analytical and immunological testing – Clotting or clotting factor level tests
Patent
1986-11-19
1988-10-25
Richman, Barry S.
Chemistry: analytical and immunological testing
Clotting or clotting factor level tests
73 641, 128673, 422 73, G01N 3386, G01N 700
Patent
active
047804181
ABSTRACT:
A method and apparatus are disclosed for measuring the aggregation of blood platelets or the coagulation of blood, the apparatus including a capillary tube for drawing blood, a piston in communication with the capillary tube and connected to a motor means for linear displacement thereof, a pressure sensor in the space located between the drawn blood and piston, and a computing means or microprocessing means for comparing the sensed pressure from the pressure sensor with a predetermined value, and providing a measured regulating output to the motor means. The method for measuring the aggregation of blood platelets and coagulation of blood includes the steps of drawing blood into the capillary tube of the moveable piston until the desired pressure is achieved within the capillary tube, and allowing the computing means to then maintain by adjustment of the piston position the pressure within the capillary tube. The computing means is able to determine the amount of blood flowing into the capillary tube during constant pressure regulation, and hence the amount of aggregate of blood platelets and blood coagulation due to a known relationship relating movement of the piston to blood drawn into the cylinder.
REFERENCES:
patent: 3911728 (1975-10-01), Fixot
patent: 4201222 (1980-05-01), Haase
Hill Jr. Robert J.
O'Brien Anthony A.
Richman Barry S.
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