Optics: measuring and testing – By particle light scattering – With photocell detection
Patent
1985-08-27
1988-08-09
Willis, Davis L.
Optics: measuring and testing
By particle light scattering
With photocell detection
250574, 356246, 356341, 422 64, 422 73, 436164, G01N 2151, G01N 33557, G01N 3502
Patent
active
047624132
ABSTRACT:
A coherent laser light flux is projected into a cell made of transparent quartz and light scattered from particles suspended in an antigen-antibody reaction liquid contained in the cell is detected by a photomultiplier by means of a collimator. An output electrical signal from the photomultiplier is sampled at different time instances and samplings are supplied to a fast Fourier transformer to derive a plurality of power spectrum densities of fluctuation in intensity of the scattered light. A plurality of power spectrum densities are averaged to generate a mean power spectrum density. An amount of antigen contained in the reaction liquid is measured in accordance with the mean power spectrum density.
REFERENCES:
patent: 3842252 (1974-10-01), Jakeman et al.
patent: 4158234 (1979-06-01), Grandchamp
patent: 4305925 (1981-12-01), Kapmeyer et al.
Davi, "Application of a Laser Self-beat Spectroscopic Technique . . . ", J. Chem. Soc. Faraday Trans. II (GB), vol.-70, pp. 700-708, 1974.
Alon et al., "Improving Light Beating Experiments by Dust Discrimination", Rev. Sci. Instrum. vol. 46, No. 4 pp. 388-390, Apr. 1975.
Cohen et al., "Immunoassay by Light Scattering Spectroscopy", Immunochemistry, vol. 12, pp. 349-351, 1975.
Article entitled "Specific Protein Analysis by Light-Scatter Measurement with a Miniature Centrifugal Fast Analyzer", by T. O. Tiffany, J. M. Parella, W. F. Johnson and C. A. Burtis.
Ando Outaro
Karaki Kouichi
Nagasaki Tatsuo
Namba Akihiro
Ohno Masahiro
Koren Matthew W.
Olympus Optical Co,. Ltd.
Willis Davis L.
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