Method and apparatus for measuring immunological reaction with t

Optics: measuring and testing – For size of particles – By particle light scattering

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356351, 356364, G01N 3350, G01N 2121, G01N 2151, G01N 1502

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047997966

ABSTRACT:
In order to measure the antigen-antibody reaction, a linearly polarized laser light beam is divided into first and second light beams and the first light beam is made incident upon a cell containing a reaction liquid including particles. The second light beam is phase-modulated by an optical phase-modulator with a phase-modulating angular frequency .omega..sup.0. A phase-modulated light beam emanating from the phase-modulator is made incident upon a photodetector together with light scattered by agglutinated particles via an analyzer having a polarization plane perpendicular to that of the linearly polarized light beam. An output signal of the photodetector is synchronously detected with a reference signal having a frequency of m.omega..sub.0 /2.pi., where m is a natural number.

REFERENCES:
patent: 4233664 (1980-11-01), Grandchamp
patent: 4480916 (1984-11-01), Bareket et al.
patent: 4725140 (1988-02-01), Musha

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