Chemistry: physical processes – Physical processes – Crystallization
Patent
1979-03-26
1980-01-01
Marantz, Sidney
Chemistry: physical processes
Physical processes
Crystallization
422 57, 422 58, 422102, 424 12, 435 7, G01N 3316
Patent
active
041815017
ABSTRACT:
A diagnostic device is described employing a solid, rigid diagnostic substrate (having as a part thereof an exposed layer of first immunologically reactive biological particles) in combination with means spaced therefrom for containing a solution of second immunologically reactive biological particles specific to the first particles. Preferably these elements are arranged with the layer of first immunologically reactive biological particles on a glass slide having a metallized surface and facing the containing means with spacing therebetween. This spacing defines a wedge-shaped volume for containing test fluid. With a test fluid in place, after allowing diffusion to occur for a predetermined period of time, the extent of formation of a layer of the second particles (i.e., a second layer) on the first layer is determined. If such a second layer develops, this determination can be related to the concentration of first particles in the test fluid. Presence of the second layer is visible with good contrast to the unaided eye.
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Hubert, T. S. Britton, "Hydrogen Ions", vol. I, 339-342, D. Van Nostrand, New York, 1943.
Giaever Ivar
Keese Charles R.
Ward, III William J.
Cohen Joseph T.
General Electric Company
MaLossi Leo I.
Marantz Sidney
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