Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system
Reexamination Certificate
2007-04-17
2007-04-17
Shrivastav, Brij B. (Department: 2859)
Electricity: measuring and testing
Particle precession resonance
Using a nuclear resonance spectrometer system
C324S318000
Reexamination Certificate
active
11401795
ABSTRACT:
Enhanced nuclear polarization of a magnetic resonance sample provides greater detection sensitivity over conventional NMR spectroscopy due to a method and an apparatus of increasing the detection sensitivity. Molecules capable of forming photo-excited triplet states are combined in a solution with a NMR sample. While in a uniform magnetic field the solution is frozen, optical radiation is applied to produce photo-excited triplet states molecules and a microwave radiation is applied to stimulate transitions of one of the triplet lines producing dynamic polarization of the nuclei in the magnetic resonance sample. The frozen sample is then rapidly melted and a NMR analysis is performed.
REFERENCES:
patent: 3475680 (1969-10-01), Anderson et al.
patent: 5023555 (1991-06-01), Ehnholm
patent: 6008644 (1999-12-01), Leunbach et al.
patent: 6108574 (2000-08-01), Ardenkjaer-Larsen
patent: 6466814 (2002-10-01), Ardenkjaer-Larsen et al.
patent: 6515260 (2003-02-01), Anderson
patent: 2002/0107439 (2002-08-01), Hersman et al.
patent: 2005/0107696 (2005-05-01), Griffin et al.
patent: 2005/0245815 (2005-11-01), Hersman et al.
patent: 2006/0192559 (2006-08-01), Ardenkjaer-Larsen et al.
Article by Ardenkjaer-Larsen, Jan et al., entitled “Increase in signal-to-Noise Ratio >10,000 Times in Liquid-State NMR”, published by PNAS,Sep. 2, 2003, vol. 100, No. 18, pp. 10158-10163.
Article by Wolber, et al., entitled “Generating Highly Polarized Nuclear Spins in Solution using Dynamic Nuclear Polarization”, published in Nuclear Instruments and Methods in Physics Research, A526 (2004), pp. 173-181.
Article by Henstra, A. et al., entitled “High Dynamic Nuclear Polarization at Room Temperature”, published by Chemical Physics Letters, vol. 165, No. 5, Jan. 5, 1990, pp. 6-10.
Article by Hausser, KH et al., entitled “Optical Spin Polarization in Molecular Crystals”, published by Advances in Magnetic Resonance, vol. 8, pp. 83-121 (1976).
Article by Bensasson, RV et al., entitled “Benzophenone Triplet Properties in Acetonitrile and Water”, published by JCS Faraday 1, 1980, 76, pp. 1801-1810.
Article by Blank A, et al. entitled “Interaction between Polarized Triplets and Stable Radicals in Liquid Solutions”, published by J. Phys.Chem A, vol. 105, No. 20, 2001, pp. 4799-4806.
Anderson Weston
Gibson Atholl
Fishman Bella
Shrivastav Brij B.
Varian Inc.
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