Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-03-21
1996-10-08
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 732, 435 5, 422 56, G01N 3353, G01N 33569
Patent
active
055630405
ABSTRACT:
A method and apparatus for detecting incipient fungal decay in wood is described. Anti-xylanase monoclonal antibody is immobilized in a defined capture zone to a polyester assay substrate. Anti-hemicellulase polyclonal-labeled latex particles (carrier zone) are applied at a position distant from the capture zone. Wood extract to be tested is applied to the end of the polyester substrate and allowed to flow laterally through the carrier zone and the capture zone. A positive test results when antigen in the wood extract is complexed by the labeled polyclonal and monoclonal antibodies to form an observable particle complex.
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Clausen, C. A., Green III, F & Highley, T. L. "Characterization of Monoclonal Antibodies to Wood-Derived .beta.-1,4-xylanase of Postia placenta & their application to detection of Incipient Decay," Wood Science & Technology (27:219-228, 1993).
Clausen, C. A., Green III, F & Highley T. L., "Early Detection of Brown-Rot Decay in Southern Yellow Pine Using Monoclonal Antibodies" In: Rossmoore, H. W., ed. Biodeterioration & Biodegradation 8: Proc. of the 8th Int'l Biodet. & Biodeg. Symposium; 1990 Aug. 26-31; Windso, On Canada, New York: Elsevier Applied Science; 1991: 412-414.
Clausen, C. A., "Enzyme Immunoassay to Detect Postia placenta in Field Tests Comparison of plate ELISA with Hydrophobic Cloth & Cotton Dipsticks," The Int'l Research Group on Wood Preservation 22nd Annual Mtg. Mar. 21, 1991 Doc. No. IRE/WP/2378, 8 pgs.
Clausen, C. A. Green III, F & Highley, T. L., "Cross-blot: A Rapid Screening Procedure for Determining Specificity of Antibodies to Native Proteins of the Brown-Rot fungus Postia placenta", FEMS Microbiology Letters, 78 (1991) 315-318.
Clausen Carol A.
Green, III Frederick
Fado John D.
Housel James C.
Portner Ginny Allen
Silverstein M. Howard
Stockhausen Janet I.
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