Method and apparatus for governing the reaction rate of enzymati

Details Method and apparatus for governing the reaction rate of enzymati Method and apparatus for governing the reaction rate of enzymati

1975-05-29

1977-04-05

Penland, R. B.

Textiles: fiber preparation

195116, 195127, 204 1T, 204195B, C12B 100

Patent

active

040160440

ABSTRACT:
Heterogeneous enzymatic catalysis is carried out by means of an enzymatic electrode comprising an enzyme fixed to a solid, conductive support. To govern the reaction rate during continuous transformation of a substrate, the enzymatic activity is regulated by adjusting the potential of the enzyme support so as to transform the substrate at a given rate. The electrode is provided with a particulate enzymatic mass operatively associated with an inert working electrode for contact with this mass to thereby subject the particles thereof to the adjustable potential. Continuous movement of a liquid reaction system is produced so as to provide intimate contact thereof with each particle of the mass, which may be arranged as a fixed bed, an agitated bed or a fluidized bed. The potential of the enzyme support is caused to continually alternate between two levels while adjusting the mean value thereof so as to maintain a corresponding mean enzymatic activity for transforming the substrate at the desired rate.

REFERENCES:
patent: 3542662 (1970-11-01), Hicks et al.
patent: 3623960 (1973-12-01), Williams
patent: 3753725 (1973-08-01), Williams et al.
patent: 3776819 (1971-11-01), Williams
patent: 3919052 (1975-11-01), Fresnel et al.

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