Surgery – Truss – Pad
Patent
1989-01-10
1989-12-19
Kamm, William E.
Surgery
Truss
Pad
A61B 502
Patent
active
048876089
ABSTRACT:
The coronary sinus is intermittently occluded by use of means for occluding the sinus, a pressure transducer for sensing the fluid pressure within the sinus and providing corresponding fluid pressure signals, and a controller responsive to the transducer and arranged to provide trigger signals to the occluding means to trigger an occlusion and to interrupt the occlusion, the system being characterized in that the controller is arranged to estimate a plateau level of the fluid pressure during each occlusion and for providing a trigger signal to interrupt each occlusion on the basis of the estimate. The duration of the interruption before the next occlusion is controlled in response to the volume flow in the sinus during the interruption. Pharmacological agents are injected into the sinus during the occlusion, for retroprofusion to the heart tissue. An analysis of heart function is obtained by analyzing the local pressure maxima in successive heartbeats during occlusion. Initiation of the next occlusion is times based on fluid pressure signals taken from the sinus during occlusion. The degree of tissue at risk of infarction (pr the amount of infarcted tissue) is estimated based on the fluid pressure signals.
REFERENCES:
patent: 3132643 (1964-05-01), Baum et al.
patent: 3847142 (1974-11-01), Williams, Jr. et al.
patent: 3951140 (1976-04-01), Eggleton et al.
patent: 3985123 (1976-10-01), Herzlinger
patent: 4009815 (1978-01-01), Lee
patent: 4016871 (1977-04-01), Schiff
patent: 4175264 (1979-11-01), Schiff
patent: 4459977 (1984-07-01), Pizon et al.
patent: 4592364 (1986-06-01), Pinto
Geary et al., "Quantitative Assessment of Infarct Size Reduction by Coronary Venous Retroperfusion in Baboons", The American Journal of Cardiology, vol. 50, Dec. 1982, pp. 1424-1430.
Mohl et al., "Effects of Intermittent Coronary Sinus Occlusion (ICSO) on Tissue Parameters After Ligation of LAD", 11th Europ. Conf. Microcirculation, 1980, No. 20, pp. 517-520.
Deboer et al., "Autoradiographic Method for Measuring the Ischemic Myocardium at Risk: Effects of Verapamil on Infarct Size After Experimental Coronary Artery Occlusion", Proc. Natl. Acad. Sci., U.S.A., vol. 77, No. 10, Oct. 1980, pp. 6119-6123.
Aerelis et al., "Attempts to Increase the Blood Supply to an Accutely Ischemic Area of the Myocardium by Intermittent Occlusion of the Coronary Sinus", (Preliminary Results), Medical Research Engineering, Dec. 4, 1977, pp. 4-7.
Meerbaum et al., "Diastolic Retroperfusion of Acutely Ischemic Myocardium", The American Journal of Cardiology, vol. 37, Mar. 31, 1976, pp. 587-598.
Moll, "Revaskularisation des ischamischen Herzmuskels bei disseminterter Koronarsklerose", Zscr. inn. Med., Jahrq. 30, 1975, Heft 1, pp. 10-14.
Mohl Werner
Tolkoff Marc J.
Boston Scientific Corporation
Kamm William E.
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