Surgery – Truss – Pad
Patent
1990-01-22
1992-07-21
Smith, Ruth S.
Surgery
Truss
Pad
128395, 128398, A61B 600
Patent
active
051313987
ABSTRACT:
A method and apparatus for distingishing cancerous tumors and tissue from benign tumors and tissue or normal tissue using native fluorescence. The tissue to be examined is excited with a beam of monochromatic light at 300 nanometers (nm). The intensity of the native fluorescence emitted from tissue is measured at 340 and 440 nm. The ratio of the two intensities is then calculated and used as a basis for determining if the tissue is cancerous as opposed to benign or normal. The invention is based on the discovery that when tissue is excited with monochromatic light at 300 nm, the native fluorescence spectrum over the region from about 320 nm to 600 nm is the tissue that is cancerous and substantially different from the native fluorescence spectrum that would result if the tissue is either benign or normal. The technique is useful in invivo and in vitro testing of human as well as animal tissue.
REFERENCES:
patent: 4479499 (1984-10-01), Alfano
patent: 4930516 (1990-06-01), Alfano et al.
patent: 4957114 (1990-09-01), Zeng et al.
patent: 4981138 (1991-01-01), Deckelbaum et al.
G. C. Tang et al., Applied Optics, vol. 28, No. 12, pp. 2337-2342 (Jun. 1989).
Alfano Robert R.
Das Bidyut
Tang Guichen
Mediscience Technology Corp.
Smith Ruth S.
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