Method and apparatus for dissociating ions by electron impact

Details Method and apparatus for dissociating ions by electron impact Method and apparatus for dissociating ions by electron impact

1986-10-15

1988-03-15

Anderson, Bruce C.

Radiant energy

Ionic separation or analysis

Cyclically varying ion selecting field means

250281, 250282, B01D 5944, H01J 4926

Patent

active

047315334

ABSTRACT:
Improved methods and apparatus suitable for use in mass spectrometry are provided for dissociating ions by achieving electronic excitation of the ions using electrons. In MS-MS applications, ion dissociation is induced by electron impact on an ion beam after the beam has exited a first mass analyzer, and before the beam enters a second analyzer. An efficient method for dissociating ions is achieved by providing a low velocity ion beam traveling substantially along the axis of an RF excited multipole field, and intersecting sheet electron beams traveling transverse to the axis of the field. When used in the analysis of high molecular weight, nonvolatile molecules, the teachings of the present invention yield the extensive and reproducible fragmentation characteristics generally associated with electron ionization of lower mass, volatile molecules. The methods and apparatus of the present invention may therefore be used in conjunction with mass spectrometry to qualitatively and quantitatively analyze a significantly greater quantity of samples. The techniques of the present invention are also well suited for dissociating high-mass, even-electron ions produced by thermospray and other soft ionization techniques.

REFERENCES:
patent: 3371205 (1968-02-01), Berry
patent: 3793063 (1974-02-01), Wiley
patent: 4234791 (1980-11-01), Enke et al.
patent: 4377745 (1983-03-01), Chang
patent: 4507555 (1985-03-01), Chang
patent: 4536652 (1985-08-01), Cooks et al.

Affiliated with

Also associated with

Rating

Method and apparatus for dissociating ions by electron impact does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus for dissociating ions by electron impact, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for dissociating ions by electron impact will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1927767