Method and apparatus for displaying gene expression patterns

Details Method and apparatus for displaying gene expression patterns Method and apparatus for displaying gene expression patterns

2006-04-18

2006-04-18

Moran, Marjorie A. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S019000, C703S002000

Reexamination Certificate

active

07031847

ABSTRACT:
The present invention discloses a method for displaying gene expression patterns of multiple genes that change according to the experiment cases, where a first axis represents the genes and a second axis represents the experiment cases. The method comprises two steps. The first step consists of designating a segment along the second axis in the expression pattern data of the multiple genes. The second step comprises clustering the expression pattern data within the designated segment along the second axis based on a predetermined reference value, repeating clustering within the same cluster in a forward or reverse direction along the second axis while changing the reference value, and displaying the results according to a predetermined display format.

REFERENCES:
patent: 5889523 (1999-03-01), Wilcox et al.
patent: 6263287 (2001-07-01), Zheng et al.
Perou et al. Distinctive gene expression patterns in mammary epithelial cells and breast cancers. PNAS (Aug. 1999) vol. 96, pp. 9212-9217.
Wen et al. Large-scale temporal gene expression mapping of central nervous system development. PNAS (Jan. 1998) vol. 95, pp. 334-339.
Eisen, et al. (1998) Proc. Natl. Acad. Sci. USA 95(25):14863-8.
Guatam Das, King-Ip Lin, Heikki Mannila, Gopal Renganathan and Padhraic Smyth, “Rule Discovery From time Series”, Proceedings Fourth International Conference on Knowledge Discovery and Data Mining, Aug. 27-31, 1998, pp 16-22.
Lamonn J. Keogh and Michael J. Pazzant, “Scaling Up Dynamic Time Warping to Massive Datasets”, Principles of Data Mining and Knowledge Discovery, Third European Conference. PKDD'99, pp. 1-11.
Michael B. Easm, Paul T. Spellman, Patrick O. Brown and David Botstem, “Cluster Analysis and Display of Genome-Wide Expression Patterns”, Proc. National Academy of Science:, Proceedings of the National Academy of Sciences of USA. National Academy of Science, Washington. US. vol. 95, Dec. 1998, pp. 14863-14868.
Irving Hofman and Ray Jarvis, “Robust and Efficient Cluster Analysis Using a Shared Near Neighbours Approach”, Pattern Recognition, 1998 Proceedings, Fourteenth International Conference on Brisbane, QLD., Australia 16-20 Aug. 1998, Lost Alamitos. CA. IEEE Comput. Soc. Aug. 16, 1998, pp. 243-247.
“Description of Pirouette Algorithms”, Chemometrics Technical Note, 1993, pp. 1-4.
EPO Search Report addressed to the corresponding EP App. No. 00121116.8 dated Jul. 17, 2003.

Affiliated with

Also associated with

Rating

Method and apparatus for displaying gene expression patterns does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus for displaying gene expression patterns, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for displaying gene expression patterns will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3611756