Chemistry: analytical and immunological testing – Automated chemical analysis – Utilizing a centrifuge or compartmented rotor
Patent
1982-04-07
1984-09-04
Skaggs, H. Grant
Chemistry: analytical and immunological testing
Automated chemical analysis
Utilizing a centrifuge or compartmented rotor
422 72, 422100, 422102, 436180, G01N 930
Patent
active
044697937
ABSTRACT:
A rotor (1) for performing a chemical reaction such as biological analysis with a sample liquid comprises: a rotatable container (2) having a vertical axis of rotation; a radially inner basin having radial partitions (4) dividing the basin into a plurality of compartments (3) for receiving an approximately-determined volume of the sample liquid, the approximately-determined volume being greater than the predetermined dose; a plurality of receptor cells (5) regularly distributed around the periphery of the rotor for receiving the liquid in the predetermined doses; and radially intermediate apparatus for conveying the liquid from the compartments to corresponding receptor cells under the effect of centrifugal force when the rotor is caused to rotate. The radially intermediate apparatus includes dispensing predetermined doses, which apparatus comprises, between each compartment (3) in the basin and a corresponding receptor cell (5), a measurement chamber (7) having an inlet orifice (6) in communication with the compartment (3), and an outlet orifice (8). The inlet and outlet orifices delimit a volume corresponding to the predetermined dose. The outlet orifice (8) leads passages (9, 10) responsive to the direction of rotation of the rotor to direct liquid issuing therefrom either to an overflow chamber (11) when the rotor is rotating in a first direction (A), or else to the receptor cell (5) when the rotor is rotating in a second, opposite direction (B).
REFERENCES:
patent: 924533 (1909-06-01), Compton et al.
patent: 3291387 (1966-12-01), Billen
patent: 3901658 (1975-08-01), Burtis
Noland Kenneth
Skaggs H. Grant
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