Surgery – Radioactive substance applied to body for therapy
Patent
1998-05-19
1999-12-14
Lacyk, John P.
Surgery
Radioactive substance applied to body for therapy
378 65, A61N 500
Patent
active
060010541
ABSTRACT:
A method for treating a site in a human body to inhibit abnormal proliferation of tissue at the site includes introducing into the body at the site a metal surface which generally conforms in shape to the shape of tissue to be treated at the site. Tissue at the site is then irradiated with ionizing radiation directed onto the metal surface from a point external to the surface so as to obtain locally enhanced radiation therapy by an amplification of the radiation dosage delivered to tissue adjacent to the metal surface as a result of backscattered radiation from the metal surface. Irradiating the tissue is performed by directing a beam of radiation with an energy content selected to have a value in a range from about 10 KeV to about 400 KeV, preferably about 40 KeV, from a point external to the body toward the metal surface and onto the tissue to be treated. The metal surface, which may be solid or composed of spaced apart particles, is selected to incorporate a metal or metal ions having an atomic number greater than 20 and of at least about 40. A synergistic effect may be achieved by employing at least one of a cytostatic drug therapy and a genetically based therapy to treat the tumor, in combination with the locally enhanced radiation therapy.
Alt Eckhard
Regulla D. F.
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