Method and apparatus for diagnosis of lead toxicity

Details Method and apparatus for diagnosis of lead toxicity Method and apparatus for diagnosis of lead toxicity

1988-02-22

1989-07-04

Howell, Janice A.

X-ray or gamma ray systems or devices

Specific application

Fluorescence

378 44, 378 49, G01N 23223

Patent

active

048457299

ABSTRACT:
Improved methods and apparatus for in vivo measurement of the skeletal lead burden of a patient and for diagnosis of lead toxicity are disclosed. The apparatus comprises an x-ray tube emitting soft low energy x-rays from a silver anode, a polarizer for polarizing the emitted x-rays, and a detector for detecting photons fluoresced from atoms in the patient's tibia upon irradiation by the polarized x-rays. The fluoresced photons are spectrally analyzed to determine their energy distribution. Peaks indicating the presence of lead are identified if the patient has relatively high bone lead content. The data may be compared to data recorded with respect to a similar test performed on patients having also had the conventional EDTA chelation tests performed thereon in order to correlate the test results with respect to a particular patient to the conventionally accepted EDTA chelation test.

REFERENCES:
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