Method and apparatus for determining the concentration of optica

Details Method and apparatus for determining the concentration of optica Method and apparatus for determining the concentration of optica

1994-03-28

1995-10-10

Pham, Hoa Q.

Optics: measuring and testing

By polarized light examination

356436, 128633, G01J 400, A61B 500

Patent

active

054575354

ABSTRACT:
In a method and apparatus for determining the concentration of optically-active substances in a fluid, such as glucose in the body fluids of a patient, two light sources are used to produce respective polarized light beams which pass through the substance to be analyzed and are incident on a detector. The second beam has a fixed polarization direction relative to the first beam. The light sources are alternatingly switched on and off at a known-frequency. A dispersing element is disposed in the path of each beam. A comparative signal is produced from the beams exiting the substance and incident on the detector. Due to the presence of the dispersive element in the path of each beam, it is possible to spectrally resolve the components of the comparative signals, so that the optical polarization contributed to the comparative signal by each substance in the fluid can be identified, and thus the concentration of a selected optically-active substance, even in the presence of multiple optically-active substances in the fluid, can be accurately identified.

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