Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2008-07-22
2008-07-22
Casler, Brian L. (Department: 3768)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S476000, C600S431000, C600S410000, C600S310000, C424S009600
Reexamination Certificate
active
10151463
ABSTRACT:
A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method.
REFERENCES:
patent: 4687325 (1987-08-01), Corby, Jr.
patent: 4687352 (1987-08-01), Igi et al.
patent: 4773097 (1988-09-01), Suzaki et al.
patent: 5202091 (1993-04-01), Lisenbee
patent: 5205291 (1993-04-01), Potter
patent: 5242441 (1993-09-01), Avitall
patent: 5319209 (1994-06-01), Miyakawa et al.
patent: 5334193 (1994-08-01), Nardella
patent: 5414258 (1995-05-01), Liang
patent: 5452723 (1995-09-01), Wu et al.
patent: 5584872 (1996-12-01), LaFontaine et al.
patent: 5594253 (1997-01-01), Bueno et al.
patent: 5636299 (1997-06-01), Bueno et al.
patent: 5637874 (1997-06-01), Honzawa et al.
patent: 5650135 (1997-07-01), Contag et al.
patent: 5661562 (1997-08-01), Aharon
patent: 5672881 (1997-09-01), Striepeke et al.
patent: 5705807 (1998-01-01), Throngnumchai et al.
patent: 5738101 (1998-04-01), Sappey
patent: 5746210 (1998-05-01), Benaron et al.
patent: 5807262 (1998-09-01), Papaioannou et al.
patent: 5812310 (1998-09-01), Stewart et al.
patent: 5818587 (1998-10-01), Devaraj et al.
patent: 5835617 (1998-11-01), Ohta et al.
patent: 5840572 (1998-11-01), Copeland et al.
patent: 5867250 (1999-02-01), Baron
patent: 5943129 (1999-08-01), Hoyt et al.
patent: 5953446 (1999-09-01), Opsal et al.
patent: 5963658 (1999-10-01), Klibanov et al.
patent: 5970164 (1999-10-01), Bamberger et al.
patent: 6069698 (2000-05-01), Ozawa et al.
patent: 6108576 (2000-08-01), Alfano et al.
patent: 6175407 (2001-01-01), Sartor
patent: 6205347 (2001-03-01), Morgan et al.
patent: 6208886 (2001-03-01), Alfano et al.
patent: 6217847 (2001-04-01), Benaron et al.
patent: 6219566 (2001-04-01), Weersink et al.
patent: 6242743 (2001-06-01), DeVito et al.
patent: 6252623 (2001-06-01), Lu et al.
patent: 6264610 (2001-07-01), Zhu
patent: 6267477 (2001-07-01), Karpol et al.
patent: 6321111 (2001-11-01), Perelman et al.
patent: 6332087 (2001-12-01), Svenson et al.
patent: 6337353 (2002-04-01), Ellis
patent: 6364829 (2002-04-01), Fulghum
patent: 6373557 (2002-04-01), Mengel et al.
patent: 6373568 (2002-04-01), Miller et al.
patent: 6381302 (2002-04-01), Berestov
patent: 6392241 (2002-05-01), Rushbrooke et al.
patent: 6394965 (2002-05-01), Klein
patent: 6403947 (2002-06-01), Hoyt et al.
patent: 6415051 (2002-07-01), Callari et al.
patent: 6429943 (2002-08-01), Opsal et al.
patent: 6529627 (2003-03-01), Callari et al.
patent: 6549288 (2003-04-01), Migdal et al.
patent: 6597931 (2003-07-01), Cheng et al.
patent: 6615061 (2003-09-01), Khalil et al.
patent: 6615063 (2003-09-01), Ntziachristos et al.
patent: 6618152 (2003-09-01), Toida
patent: 6618463 (2003-09-01), Schotland et al.
patent: 6628401 (2003-09-01), Toida
patent: 6628747 (2003-09-01), Schotland et al.
patent: 6636755 (2003-10-01), Toida
patent: 6642953 (2003-11-01), Nieto Velasco et al.
patent: 6646678 (2003-11-01), Kobayashi
patent: 6665072 (2003-12-01), Hoyt
patent: 6690466 (2004-02-01), Miller et al.
patent: 6690520 (2004-02-01), Kusuzawa
patent: 6693710 (2004-02-01), Hoyt
patent: 6710770 (2004-03-01), Tomasi et al.
patent: 6750964 (2004-06-01), Levenson et al.
patent: 6775567 (2004-08-01), Cable et al.
patent: 6813030 (2004-11-01), Tanno
patent: 6919919 (2005-07-01), Nelson et al.
patent: 6924893 (2005-08-01), Oldenbourg et al.
patent: 6963375 (2005-11-01), Lundberg
patent: 7113217 (2006-09-01), Nilson et al.
patent: 7184047 (2007-02-01), Crampton
patent: 2003/0002028 (2003-01-01), Rice et al.
patent: 2003/0099329 (2003-05-01), Schotland et al.
patent: 2004/0010192 (2004-01-01), Benaron et al.
patent: 2004/0015062 (2004-01-01), Ntziachristos et al.
patent: 2004/0021771 (2004-02-01), Stearns et al.
patent: 2004/0027659 (2004-02-01), Messerschmidt et al.
patent: 2004/0085536 (2004-05-01), Schotland et al.
patent: 2004/0262520 (2004-12-01), Schotland et al.
patent: 2005/0149877 (2005-07-01), Rice et al.
patent: 2005/0283071 (2005-12-01), Ripoll et al.
patent: 2006/0118742 (2006-06-01), Levenson et al.
patent: 2006/0119865 (2006-06-01), Hoyt et al.
patent: 2006/0146346 (2006-07-01), Hoyt
patent: 2006/0173354 (2006-08-01), Ntziachristos et al.
patent: 2006/0245631 (2006-11-01), Levenson
patent: 2007/0016078 (2007-01-01), Hoyt et al.
patent: 1 016 419 (2000-07-01), None
patent: WO 97/40381 (1997-10-01), None
patent: WO 98/34533 (1998-08-01), None
patent: WO 98/34533 (1998-08-01), None
patent: WO 00/17643 (2000-03-01), None
patent: WO 00/36106 (2000-06-01), None
patent: WO 00/54581 (2000-09-01), None
patent: WO 01/18225 (2001-03-01), None
patent: WO 01/63247 (2001-08-01), None
patent: WO02/41760 (2002-05-01), None
Contag, C. H. et al., “Use of Reporter Genes for Optical Measurements of Neoplastic Disease in Vivo”,Neoplasia, vol. 2, No. 1-2, pp. 41-52, 2000.
Kienle, A. et al., “Noninvasive determination of the optical properties of two-layered turbid media”,Applied Optics, vol. 37, No. 4, pp. 779-791, 1998.
Benaron, David A., “System for Imaging Infection and Gene Expression in the Body in 3-D,” Biomedical Optical Spectroscopy and Diagnostics, 1998 Technical Digest, 1998, Optical Society of America, pp. 134-135.
Frohn, “Super-Resolution Fluorescence Microscopy by Structured Light Illumination,” Dissertation submitted to the Swiss Federal Institute of Technology, Zurich, 2000.
Rice et al., “Advances in 2D In Vivo Optical Imaging Instrumentation,” Abstract No. 186, Society for Molecular Imaging 2ndAnnual Meeting, Aug. 2003.
Achilefu et al., “Novel Receptor-Targeted Fluorescent Contrast Agents for In Vivo Tumor Imaging”, Investigative Radiology, vol. 35(8), Aug. 200, pp. 479-485.
Arridge, “Photon-Measurement Density Functions. Part 1: Analytical Forms”, Applied Optics, vol. 34, No. 31, Nov. 1, 1995, pp. 7395-7409.
Arridge, “Photon-Measurement Density Functions. Part 2: Finite-Element-Method Calculations”, Applied Optics, vol. 34, No. 34, Dec. 1, 1995, pp. 8026-8037.
Becker et al., “receptor-Targeted Optical Imaging of Tumors with Near-Infrared Fluorescent Ligands”, Nature Biotechnology, vol. 19, Apr. 2001, pp. 327-330.
Bevilacqua et al., “Monte Carlo Study of Diffuse Reflectance at Source-Detector Separations Close to One Transport Mean Free Path”, Optical Society of America, vol. 16, No. 12, Dec. 1999, pp. 2935-2945.
Bouvet et al., “Real-Time Optical Imaging of Primary Tumor Growth and Multiple Metastic Events in a Pancreatic Cancer Orthotopic Model”, Cancer Research, vol. 62, Mar. 1, 2002, pp. 1534-1540.
Chang et al., “Improved Reconstruction Algorithm for Luminescence Optical Tomography When Background Lumiphore is Present”, Applied Optics, vol. 37, No. 16, Jun. 1, 1998, pp. 3547-3552.
Cheong et al., “A review of the Optical Properties of Biological Tissues”, IEEE Journal of Quantum Electronics, vol. 26, No. 12, Dec. 1990, pp. 2166-2185.
Contag et al., “Photonic Detection of Bacterial Pathogens in Living Hosts”, Molecular Microbiology, vol. 18, No. 4, 1995, pp. 593-603.
Eppstein et al., “Biomedical Optical Tomography Using Dynamic Parameterization and Bayesian Conditioning on Photon Migration Measurements”, Applied Optics, vol. 38, No. 10, Apr. 1, 1999, pp. 2138-2150.
Francis et al, “Visualizing Pneumococcal Infections in the Lungs of Live Mice Using
Rice Bradley W.
Stearns Daniel G.
Troy Tamara L.
Beyer Law Group LLP
Casler Brian L.
Cattungal Sanjay
Xenogen Corporation
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