Method and apparatus for determining platelet function in primar

Details Method and apparatus for determining platelet function in primar Method and apparatus for determining platelet function in primar

1994-07-11

1996-06-04

Warden, Robert J.

Chemistry: analytical and immunological testing

Clotting or clotting factor level tests

436 63, 422 73, 422 99, 422102, 435 2, 4352879, 4352881, G01N 3386

Patent

active

055232388

ABSTRACT:
A method for determining a platelet function in a primary hemostasis is provided in which a blood sample or a platelet containing fraction thereof is introduced into a vessel having a flat bottom which has an inner surface covered with a substrate capable of inducing platelet adhesion thereto and aggregation such as ECM (extracellular matrix). Preparation is then rotated inside the vessel, and consequently shear forces develop on the surface which bring to adhesion an aggregation of the blood platelets to the surface. Morphological parameters of blood aggregates are then determined.

REFERENCES:
patent: 4880788 (1989-11-01), Moake et al.
Riess et al., American Journal of Clinical Pathology, vol. 85, No. 1, pp. 50-56, Jan. 1986.
Tippe et al. Thrombosis Research, vol. 67, No. 4, pp. 407-418, 1992.
Born, Nature, vol. 194, pp. 927-929, Jun. 9, 1962.
Fukuyama et al., Thrombosis Research, vol. 54, No. 3, pp. 253-260, 1989.
Ikeda et al., Journal of Clinical Investigation, vol. 87, pp. 1234-1240, Apr. 1991.
Lavee et al., Journal of Thoracic+Cardiovascular Surgery, vol. 97, No. 2, pp. 204-212, Feb. 1989.

Affiliated with

Also associated with

Rating

Method and apparatus for determining platelet function in primar does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus for determining platelet function in primar, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for determining platelet function in primar will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-382876