Radiant energy – Invisible radiant energy responsive electric signalling – With or including a luminophor
Patent
1983-09-06
1985-11-26
Smith, Alfred E.
Radiant energy
Invisible radiant energy responsive electric signalling
With or including a luminophor
250328, 250369, G01T 1204
Patent
active
045556296
ABSTRACT:
A method for ascertaining radiochemical homogeneity in a liquid scintillation sample reliably identifies inaccurate geometries is disclosed so that meaningful activity counts can be determined. The novel method involves measuring the activity level of a set of homogeneous quench standard to obtain quench indicating parameter, or the Spectral Index of the External standard (SIE). The endpoint of each standard sample is computed allowing the formation of a table so that a calibration curve for each radionuclide of interest can be computed. The activity level of the unknown sample is then measured and the SIE determined so that an endpoint can be calculated. Finally, the theoretical endpoint obtained from a calibration curve is compared to the computed endpoint; if the computed endpoint of the sample deviates by more than 4% for tritium and 5% for higher energy radionuclides from the theoretical endpoint, the sample is considered to be nonhomogeneous or heterogeneous. An external standard-type liquid scintillation counting system is disclosed which automatically determines sample homogeneity, and it includes a microprocessor in its control system. The steps of the present invention and incorporated into the programmed steps for the microprocessor such that nonhomogeneous or heterogeneous samples are automatically identified on the readout of the system for an investigator.
REFERENCES:
patent: 3979503 (1976-09-01), Kaartinen
patent: 3999070 (1976-12-01), Tarkkanen
patent: 4002909 (1977-01-01), Packard et al.
patent: 4029401 (1977-06-01), Nather
patent: 4315151 (1982-02-01), Horrocks
Horrocks et al, "Common Problems in Sample Preparation for Liquid Scintillation Counting", Laboratory Practice, vol. 30, No. 5, May 1981.
Horrocks et al, "Instrumental Methods for Detecting Some Common Problems in Liquid Scintillation Counting", Laboratory Practice, vol. 30, No. 5, May 1981.
E. T. Bush, "A Double Ratio Technique as an Aid to Selection of Sample Preparation Procedures in Liquid Scintillation Counting", International Journal of Applied Radiation and Isotopes, 1968, vol. 19.
Everett et al, "The Application of Spectral Analysis in Liquid Scintillation Counting", Liquid Scintillation Counting Recent Applications and Development, vol. 1, Physical Aspects.
Fox, "Recent Advances in Sample Preparation", Liquid Scintillation Counting Recent Applications and Development, vol. II, Sample Preparation and Applications.
Bransome, Jr. et al, "Local Absorption of Low Energy Betas by Solid Supports: A Problem in Heterogeneous Counting".
DeFilippis et al, "Dual Label Determination of Tritium and Iodine-125 by Liquid Scintillation Counting", Techniques & Applications of Liquid Scintillation Counting-1.
DeFilippis Stanley J.
Everett Leroy J.
Fields Carolyn E.
Hayter Robert P.
Packard Instrument Company Inc.
Smith Alfred E.
LandOfFree
Method and apparatus for determination of sample homogeneity in does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus for determination of sample homogeneity in , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for determination of sample homogeneity in will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-271167