Combinatorial chemistry technology: method – library – apparatus – Method of creating a library
Reexamination Certificate
2004-09-03
2010-02-16
Lundgren, Jeffrey S. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method of creating a library
C422S082050, C435S005000, C435S006120, C435S007100, C435S007200
Reexamination Certificate
active
07662751
ABSTRACT:
Detection apparatus for use in the detection of the presence of a selected pathogen in a sample are disclosed. Such apparatus include: a substrate with a detection region on a surface thereof, the detection region having microstructures including grooves formed therein that will align liquid crystal material in contact therewith, the width and depth of the grooves being in the range of 10 μm or less; a blocking layer on the surface of the detection region of the substrate that does not disrupt the alignment of liquid crystal material in contact therewith, the blocking layer blocking nonspecific adsorption of pathogens to the surface; and a binding agent on the surface of the detection region of the substrate, the binding agent specifically binding the selected pathogen.
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Abbott Nicholas L.
Skaife Justin J.
Foley & Lardner LLP
Lundgren Jeffrey S.
Wisconsin Alumni Research Foundation
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