Method and apparatus for detecting radiation

Details Method and apparatus for detecting radiation Method and apparatus for detecting radiation

2005-08-23

2005-08-23

Lauchman, Layla (Department: 2877)

Optics: measuring and testing

For light transmission or absorption

C356S436000, C250S459100, C378S044000

Reexamination Certificate

active

06934030

ABSTRACT:
In analyzing radiation from a sample, single-quanta counting can be used to advantage especially at low levels of radiation energy, e.g. in the detection of fluorescent radiation. Preferred detection techniques include methods in which (i) fluorescence-stimulating radiation is intensity-modulated in accordance with a preselected code, (ii) wherein it is the fluorescent radiation which is intensity-modulated with the preselected code, and (iii) wherein modulation with a preselected code is applied to a sample to influence a property which functionally affects emitted fluorescent radiation. For registration of the signals from a sensing element of a single-photon detector, time of arrival is recorded, optionally in conjunction with registration of time intervals. Advantageously, in the interest of minimizing the number of pulses missed due to close temporal spacing of pulses, D-triggers can be included in counting circuitry.

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