Method and apparatus for detecting immunologically reactive biol

Details Method and apparatus for detecting immunologically reactive biol Method and apparatus for detecting immunologically reactive biol

1974-04-01

1976-06-01

Wolk, Morris O.

Chemistry: physical processes

Physical processes

Crystallization

23253R, 23253TP, 23259, 1951035R, 195127, 424 12, G01N 3316

Patent

active

039604918

ABSTRACT:
A metallized solid substrate is covered with a moistened porous paper, and specimens of first and second solutions suspected of respectively containing first and second immunologically reactive biological particles specific to each other are applied to selected areas of the paper and allowed to diffuse therein. Presence of the first and second biological particles in the solutions is indicated with high sensitivity by formation of a complexed protein precipitate line on the metallized substrate along the region of intersection of the two diffused particles and which is visible with good contrast to the unaided eye.

REFERENCES:
patent: 3390962 (1968-07-01), Goldsmith
patent: 3674438 (1972-07-01), Shen
patent: 3692491 (1972-09-01), Trentelman
patent: 3709661 (1973-01-01), Hubscher
patent: 3718436 (1973-02-01), Ushakoff
patent: 3725004 (1973-04-01), Johnson
patent: 3853467 (1974-12-01), Giaever

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