Chemistry: physical processes – Physical processes – Crystallization
Patent
1978-07-20
1980-09-16
Marantz, Sidney
Chemistry: physical processes
Physical processes
Crystallization
23915, 250365, 250458, 250461B, 424 8, 424 12, G01N 3316, G01N 2100
Patent
active
042227437
ABSTRACT:
A metal-covered substrate is first adsorbed with a layer of known biological particles. This active substrate is then put into a solution containing an unknown amount of second biological particles that will bind the first kind of particles which are randomly distributed in the layer. A third biological particle bound to a fluorescent dye is applied to this substrate which is then placed in an apparatus having a light source inducing fluorescent emission, and a photon counting system to measure the amount of fluorescent photon. The metal-covered substrate reflects the exciting photon toward a photon trap so that few exciting photons will go to the photon counting system, while the induced signal is reflected toward the photon counting system and more induced signal will be measured.
REFERENCES:
patent: 3876504 (1975-04-01), Koffler
patent: 3904367 (1975-09-01), Golibersuch
patent: 3979184 (1976-09-01), Gidever
patent: 3998943 (1976-12-01), Ullman
patent: 4011308 (1977-03-01), Gidever
patent: 4020151 (1977-04-01), Bolz
patent: 4036946 (1977-07-01), Kleinerman
patent: 4056724 (1977-11-01), Harte
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