Method and apparatus for detecting biological activities in a sp

Details Method and apparatus for detecting biological activities in a sp Method and apparatus for detecting biological activities in a sp

1990-03-29

1993-11-30

Griffin, Ronald W.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

435291, 435289, 435165, 435805, 435 35, C12M 100

Patent

active

052664864

ABSTRACT:
A method, a sensor and apparatus for detecting biological activities in a specimen, for example in a blood sample, are provided in which a sealable container is sealed with a culture medium therein into which the sample is introduced, metabolic processes are enhanced in the presence of microorganisms in the sample and changes taking place in the concentrations of the substances such to such processes are detected and monitored with an excitation and detection assembly assigned to concentration sensors, herein the form of optodes which are optically coupled to the excitation and detection assembly and thereby to an evaluation unit for determining concentration changes of the substances over time as indications of the presence of microorganisms.

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patent: 4608344 (1986-08-01), Carter et al.
patent: 4810655 (1989-03-01), Khalil et al.
patent: 4945060 (1990-07-01), Turner et al.
patent: 4953980 (1990-09-01), De Volk et al.
patent: 5043286 (1991-08-01), Khalil et al.
MacFaddin, J. F. "Urease Test", Biochemical Tests for Identification of Medical Bacteria, The Williams & Wilkins, Company, 1976, pp. 187-194.
MacFaddin, J. F. "Klinger's Ironagar/Triple Sugarironagar Tests," The Williams & Wilkins Company 1976, pp. 108-118.

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