Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2011-01-11
2011-01-11
Lin, Jerry (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
Reexamination Certificate
active
07869960
ABSTRACT:
Provided are a method and apparatus for detecting bio-complexes that are important sub protein interaction networks using a rule-based template in large interaction networks present in a single species. The method includes (a) defining a rule-based template corresponding to a bio-complex to be detected by defining a node that consists of at least one protein, a triplet that consists of two defined nodes and a protein interaction relationship therebetween, and single and composite rules using the triplet and an operator; (b) analyzing the rules of the defined rule-based template by analyzing whether the protein corresponding to the node included in the defined rule-based template and the protein interaction relationship corresponding to the triplet are present in a protein interaction network; and (c) detecting a bio-complex in the protein interaction network by assessing the triplet included in the rules analyzed and the node included in the triplet using a protein interaction relationship and protein of the protein interaction networks.
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T. Oyama et al., Extraction of knowledge on protein-protein interaction by association rule discovery, Bioinformatics, vol. 18, No. 5, 2002, pp. 705-714.
Choi Jae Hun
Park Jong Min
Park Seon Hee
Electronics and Telecommunications Research Institute
Lin Jerry
Lowe Hauptman & Ham & Berner, LLP
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