Method and apparatus for depositing samples on a target surface

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C250S281000, C250S287000, C422S063000, C422S105000

Reexamination Certificate

active

07550721

ABSTRACT:
There is provided a sample deposition device for depositing samples on a target surface such as MALDI target surfaces for use in mass spectrometry analysis. The device comprises a vacuum chamber, a sealable opening communicating with the vacuum chamber, a sample inlet and a sample outlet. The sample outlet is located in the vacuum chamber which is sealed by contact with the target surface. The sample is drawn through the sample inlet and deposited on the surface by the action of the vacuum.

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Chen, Vincent C. et al, “Device for the Reversed-Phase Separation and On-Target Deposition of Peptides Incorporating a Hydrophobic Sample Barrier for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry”, Analytical Chemistry, vol. 76, No. 4, Feb. 15, 2004.

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