Method and apparatus for delivery of x-ray irradiation

X-ray or gamma ray systems or devices – Beam control

Reexamination Certificate

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Reexamination Certificate

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06847700

ABSTRACT:
The subject invention pertains to a method and apparatus for generation and/or delivery of x-ray irradiation. The subject invention can be used to deliver x-ray irradiation to an artery in order to prevent restenosis in the artery. For example, a short pulse laser generated ionizing dose of x-ray irradiation can be effectively delivered to the arterial wall using hollow waveguides. The delivery of such a dose can help to prevent restenosis. The use of short pulse x-rays can allow energy to be precisely delivered, and can reduce diffusion of the energy to nearby normal tissue during the exposure. The arterial walls can be irradiated from a cylindrical or conical symmetric mirrored reflective end tip mounted on the end of a hollow waveguide. The subject invention also pertains to a method and apparatus for delivery of x-ray radiation with respect to medical therapies such as tumor necrosis.

REFERENCES:
patent: 5001737 (1991-03-01), Lewis et al.
patent: 5101422 (1992-03-01), Thiel et al.
patent: 5327446 (1994-07-01), Waynant
patent: 5370608 (1994-12-01), Sahota et al.
patent: 5707332 (1998-01-01), Weinberger
patent: 5866914 (1999-02-01), Jones
patent: 5916143 (1999-06-01), Apple et al.
patent: 6093141 (2000-07-01), Mosseri et al.
patent: 6504901 (2003-01-01), Loxley et al.
Bittl, John A. et al., “Clinical Success, Complications and Restenosis Rates with Excimer Laser Coronary Angioplasty,” American Journal of Cardiology, 1992, pp. 1533-1539, vol. 70.
Cattaneo, Carlo et al., “A Form of Heat Conduction Equation Which Eliminates the Paradox of Instantaneous Propagation,” Comptes Rendus, 1958, pp. 431-433, vol. 247.
Coursey, B.M. et al., “Radionuclide Therapy,” Physics Today, Apr. 2000, pp. 25-30.
De Jaegere, P. et al., “Endovascular Stents: Preliminary Clinical Results and Future Developments,” Clinical Cardiology, 1993, pp. 369-378, vol. 16.
Ellis, S.G. et al., “Restenosis after Placement of Palmaz-Schatz Stents in Native Coronary Arteries: Initial Results of Multicenter Experience,” Circulation, 1992, pp. 1836-1844, vol. 86.
Gannot, Israel et al., “Current Status of Flexible Waveguides for IR Laser Radiation Transmission,” IEEE Journal of Selected Topics in Quantum Electronics, 1986, pp. 880-889, vol. 2 No. 4.
Ilev, Ilko K. et al., “All-Fiber-Optic Sensor for Liquid Level Measurement,” Review of Scientific Instruments, 1999, pp. 2551-2554, vol. 70 No. 5.
Ilev, Ilko K. et al., “Grazing-Incidence-Based Hollow Taper for Infrared Laser-to-Fiber Coupling,” Applied Physics Letters, 1999, pp. 2921-2923, vol. 74 No. 20.
Ilev, Ilko K. et al., “Ultraviolet Laser Delivery Using an Uncoated Hollow Taper,” IEEE Journal of Quantum Electronics, Aug. 2000, pp. 944-948, vol. 36 No. 8.
Joseph, D.D. et al., “Heat Waves,” Reviews of Modern Physics, Jan. 1989, pp. 41-73, vol. 61 No. 1.
Kaminski, W., “Hyperbolic Heat Conduction Equation for Material with a Nonhomogeneous Inner Structure,” Journal of Heat Transfer, Aug. 1990, pp. 555-560, vol. 112.
Kim, W.S. et al., “Hyperbolic Heat Conduction Due to Axisymmetric Continuous or Pulse Surface Heat Sources,” Journal of Applied Physcis, Dec. 1990, pp. 5478-5485, vol. 68.
Kuczumow, Andrzej et al., “Scheme for X-Ray Tracing in Capillary Optics,” Appled Optics, Dec. 1994, pp. 7928-7932, vol. 33 No. 34.
Kumakhov, M.A. et al., “Multiple Reflection From Surface X-Ray Optics,” Physics Reports, 1990, pp. 289-350, vol. 191 No. 5, North-Holland.
Kumar, Sunil et al., “Hyperbolic Damped-Wave Models for Transient Light-Pulse Propogation in Scattering Media, ” Applied Optics, Jul. 1996, pp. 3372-3378, vol. 35 No. 19.
Kumar, Sunil et al., “Microscale Aspects of Thermal Radiation Transport and Laser Applications,” Advances in Heat Transfer, 1999, pp. 187-294, vol. 33, Academic Press, San Diego.
Matsuura, Yuji et al., “Delivery of F2—excimer Laser Light by Aluminum Hollow Fibers,” Optics Express, Jun. 2000, vol. 6 No. 13.
Mitra, Kunal et al., Development and Comparison of Models for Light-Pulse Transport through Scattering-Absorbing Media, Jan. 1999, pp. 188-196, vol. 38 No. 1.
Mitra, K. et al., “Experimental Evidence of Hyperbolic Heat Conduction in Processed Meat,” Journal of Heat Transfer, 1995, pp. 568-573, vol. 117 No. 3.
Mosher, D. et al., “X radiation from High-Energy-Density Exploded-Wire Discharges,” Applied Physics Letter, Oct. 1973, pp. 429-430, vol. 23 No. 8.
Mosher, D. et al., “X-Ray Light Pipes,” Applied Physics Letter, Jul. 1976, pp. 105-107, vol. 29 No. 2.
Pepine, Carl J. et al.“A Controlled Trial of Corticosteroids to Prevent Restenosis After Coronary Angioplasty,” Circulation, Feb. 1990, pp. 1753-1761, vol. 81.
Rindby, A., “Applications of Fiber Technique in the X-Ray Region,” Nuclear Instruments and Methods in Physics Research, 1986, pp. 536-540, A249, North-Holland, Amsterdam.
Schatz, Richard A.et al. “Clinical Experience With the Palmaz-Schatz Coronary Stent Initial Results of a Multicenter Study,” Circulation, 1991, pp. 148-161, vol. 83.
Serruys, Patrick W. et al. “A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease,” The New England Journal of Medicine, Aug. 1994, pp. 489-495, vol. 331 No. 8.
Teirstein, Paul S. et al., “Two-Year Follow-Up After Catherer-Bases Radiotherapy to Inhibit Coronary Restenosis,” Circulation, Jan. 1999, pp. 243-247, vol. 99 No. 2.
Topol, Eric J. et al., “A Comparison of Directional Atherectomy with Coronary Angioplasty in Patients with Coronary Artery Disease,” The New England Journal of Medicine, Jul. 1993, pp. 221-227, vol. 329 No. 4.
Vedavarz, Ali et al., “Significance of Non-Fourier Heat Wave in Conduction,” ASMW Journal of Heat Transfer, Feb. 1994, pp. 221-224, vol. 116.
Verin, Vitali et al., “Intra-arterial Beta Irradiation Prevents Neointimal Hyperplasia in a Hypercholesterolemic Rabbit Restenosis Model,” Ciculation, 1995, pp. 2284-2290, vol. 92 No. 8.
Vernotte, M.P. et al., “Les Paradoxes de la Theorie Coninue de l'Equation de la Chaleur,” Comptes Rendus, 1958, pp. 3154-3155, vol. 246.
Waksman, Ron et al., “Endovascular Low-Dose Irradiation Inhibits Neointima Fomation After Coronary Artery Balloon Injury in Swine: A Possible Role for Radiation Therapy in Restenosis Prevention,” Circulation, 1995, pp. 1533-1539, vol. 91.
Gannot, I. et al., “Broadband Flexible Waveguides for Free-Electron Laser Radiation,” Applied Optics, Sep. 1997, pp. 6289-6293, vol. 36 No. 25.
Weidermann, J.G. et al., “Intracoronary Irradiation Markedly Reduces Neointimal Proliferation After Balloon Angioplasty in Swine: Persistent Benefit at 6-Month Follow-Up,” Journal of American College of Cardiology, 1995, pp. 1451-1456, vol. 25.
Whitworth, Hall B. et al., “Effect of Nifedipine on Recurrent Stenosis After Percutaneous Transluminal Coronary Angioplasty,” Journal of American College of Cardiology, 1986, pp. 1271-1276, vol. 8 No. 6.
Iler, Ilko K. et al. “Uncoated hollow taper as a simple optical funnel for laser delivery,” Review of Scientific Instruments, Oct. 1999, pp. 3840-3843, vol. 70 No. 10.
Spiller, Eberhard et al. “Propagation of x rays in waveguides,” Appl. Phys. Lett., Jan. 1974, pp. 60-61, vol. 24 No. 2.
Berg, R. et al. “Time-resolved Transiliumination for Medical Diagnostics”Time-Resolved Spectroscopy and Imaging of Tissues, 1991, pp. 110-119, vol. 1431.
Gordon, C.L. et al. “Time-gated Imaging with an Ultrashort-pulse, Laser-product-plasma X-ray Source”Optics Letters, 1995, pp. 1056-1058, vol. 20, No. 9.
Milne, P.J. et al. “Development of Sterotactically Guided Laser Interstitial Thermotherapy of Breasr Cancer: In Situ Measurement and Analysis of th

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