Method and apparatus for de-convoluting a convoluted spectrum

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C436S173000, C435S006120

Reexamination Certificate

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11458082

ABSTRACT:
Embodiments of the present invention relate to methods, systems, and apparatus suitable for performing a survey scan of one or more analytes or labeled fragments of analytes to obtain a convoluted spectrum and to de-convolute the convoluted spectrum using, for example, a mass spectrometer and associated processing system.

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Eugster, O., et al., Identification of Isobaric Interferences. A Computer Program For Ion Microprobe Mass Spectral Data, International Journal of Mass Spectrometry and Ion Processes (1985) 66:291-312, Elsevier Science Publishers B.V., Amsterdam—Printed in The Netherlands.
Kushnir, Mark M., et al., Simultaneous quantitative analysis of isobars by tandem mass spectrometry from unresolved chromatographic peaks, ARUP Institute for Clinical and Experimental Pathology, Journal of Mass Spectrometry (2004) 39: 532-540, Wiley InterScience (www.interscience.wiley.com) DOI:10.1002/jms.619.
Simultaneous quantitative analysis of isobars by tandem mass spectrometry from unresolved chromatographic peaks, Mark M. Kushnir, Alan L. Rockwood and Gordon J. Nelson, ARUP Institute for Clinical and Experimental Pathology, Journal of Mass Spectrometry (2004) 39: 532-540.
Identification of Isobaric Interferences. A Computer Program For Ion Microprobe Mass Spectral Data, International Journal of Mass Spectrometry and Ion Processes (1985) 66:291-312.

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