Method and apparatus for controlling the uniform smearing of...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is a biological cell or cell fragment

Reexamination Certificate

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C436S527000, C436S164000, C422S051000

Reexamination Certificate

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10989172

ABSTRACT:
A method and apparatus for controlling the processing of a liquid sample, e.g., a blood sample, based on a measurement related to the sample's ability to coat a surface against which the sample is brought into contact while being routinely transported. Preferably, the sample is advanced through a tube, and the amount of sample residue remaining within the tube is measured and correlated to coating process subsequently carried out on the sample, e.g., a process for producing blood-smears on a microscope slide. In a preferred embodiment, the amount of sample residue in a blood-transport tube is used to control the motion profile (i.e., acceleration and velocity) of a drop-spreading member used to spread a blood drop on a microscope slide in an automated slide-making instrument.

REFERENCES:
patent: 5209903 (1993-05-01), Kanamori et al.
patent: 5479009 (1995-12-01), Jablonski et al.
patent: 5537203 (1996-07-01), Carr
patent: 5650332 (1997-07-01), Gao et al.
patent: 5665312 (1997-09-01), Sperber et al.
patent: 5730939 (1998-03-01), Kurumada et al.
patent: 08094441 (1996-04-01), None
patent: 3662057 (2005-06-01), None

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