Coating processes – Medical or dental purpose product; parts; subcombinations;... – Analysis – diagnosis – measuring – or testing product
Patent
1993-05-27
1995-12-12
Jones, W. Gary
Coating processes
Medical or dental purpose product; parts; subcombinations;...
Analysis, diagnosis, measuring, or testing product
427 211, 427264, 427266, 427271, 427282, 427336, 427338, 4274072, 4352851, 4353171, 4352831, 422 57, 422 58, 422 99, 422104, A01N 102, B05D 136, B05D 500, C12Q 168
Patent
active
054747961
ABSTRACT:
The invention provides apparatus and methods for making arrays of functionalized binding sites on a support surface. The invention further provides apparatus and methods for sequencing oligonucleotides and for identifying the amino acid sequence of peptides that bind to biologically active macromolecules, by specifically binding biologically active macromolecules to arrays of peptides or peptide mimetics.
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Mandenius, et al., "Reversible and Specific Interaction of Dehydrogenases with a Coenzyme-Coated Surface Continuously Monitored with a Reflectometer," Anal. Biochem 157; 283-288 (1986).
Southern and Maskos, "Analysing Nucleic Acids by Hybridisation to Arrays of Oligonucleotides: Analysis of Mutation," Abstracts of papers presented at the 1991 meeting on Genome Mapping & Sequencing p. 195, May 8-May 12, 1991, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
Drmanac et al., "Sequencing of Megabase Plus DNA by Hybridization: Theory of the Method," Genomics 4; 114-128 (1989).
Khrapko, et al., "An oligonucleotide hybridization approach to DNA sequencing," FEBS Letters 256, 118-122 (1989).
Geysen et al., "Strategies for epitope analysis using peptide synthesis," J. Immunol. Methods 102; 259-274 (1987).
Jones W. Gary
Protogene Laboratories, Inc.
Sisson Bradley L.
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