Data processing: structural design – modeling – simulation – and em – Simulating nonelectrical device or system – Biological or biochemical
Reexamination Certificate
2005-03-01
2005-03-01
Frejd, Russell (Department: 2128)
Data processing: structural design, modeling, simulation, and em
Simulating nonelectrical device or system
Biological or biochemical
C703S002000
Reexamination Certificate
active
06862561
ABSTRACT:
The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
REFERENCES:
patent: 5494668 (1996-02-01), Patwardhan
patent: 5814078 (1998-09-01), Zhou et al.
patent: 6051029 (2000-04-01), Paterson et al.
patent: 6069629 (2000-05-01), Paterson et al.
patent: 6078739 (2000-06-01), Paterson et al.
patent: 6144954 (2000-11-01), Li
patent: 6539347 (2003-03-01), Paterson et al.
patent: 20030087285 (2003-05-01), Chow et al.
Dullens et al., “A Survey of some formal models in tumor immunology”, Cancer Immunogy Immunotherapy (1986) 23:159-164.
Look et al., “Computer simulation of the cellular immune to malignant lymphoid cells: logic of approach, model design and laboratory verification”, Immunology (1981) 43:677-690.
Ateshian (1997) “A theoretical formulation for boundary friction in articular cartilage,”Journal of Biomechanical Engineering, 119:81-86.
Bogoch et al. (1998) “Abnormal bone remodeling in inflammatory arthritis,”Canadian Journal of Surgery, 41(4):264-271.
Chaplain (2000) “Mathematical modelling of antiogenesis,”Journal of Neuro-Oncology, 50:37-51.
Clift (1992) “Finite-element analysis in cartilage biomechanics,”J. Biomed. Eng., 14:217-221.
Heegaard et al. (1999) “Mechanically modulated cartilage growth may regulate joint surface morphogenesis,”Journal of Orthopaedic Research, 17(4):509-517.
Helliwell et al. (2000) “Joint symmetry in early and late rheumatoid and psoriatic arthritis,”Arthritis&Rheumatism, 43(4):865-871.
Hlavacek (1993) “The role of synovial fluid filtration by cartilage in lubrication of synovial joints—I. Mixture model of synovial fluid,”J. Biomechanics, 26(10):1145-1150.
Hlavacek (1993) “The role of synovial fluid filtration by cartilage in lubrication of synovial joints—II. Squeeze-film lubrication: homogenous filtration,”J. Biomechanics, 26(10):1151-1160.
Lane Smith et al. (2000) “Effects of shear stress on articular chondrocyte metabolism,”Biorheology, 37:95-107.
Beaupre', G.S., et al., 2000, “Mechanobiology in the Development, Maintenance, and Degeneration of Articular Cartilage”,J. Rehabil. Res. Dev., 37:145-151.
Pollatschek, M.A., et. al, 1990, “A Mathematical Model of Osteoarthosis”,J. Theor. Biol., 143:497-505.
Shi, Q., 1995, “Finite Element Analysis of Pathogenesis of Osteoarthritis in the First Carpometalcarpal Joint”,Acta Med. Okayama, 49:43-51.
Szekanecz, Z., et al., 2001, “Update on Synovitis”,Curr. Rheumatol. Rep., 3:53-63.
Wynarsky, G.T., et al., 1983, “Mathematical Model of the Human Ankle Joint”,J.Biochem., 16:241-251.
Lutzenberger, C., et al., 1998, “A Three-Dimensional Model of the Human Locomotor Apparatus for Analysis of Hemiplegic Gait”,Proc. 20thAnnual Conference of IEEE Eng. Med. Bio. Soc., 2407-2410.
Nielsen, C., et al., 1995, “A Computational Method for Comparing the Behavior and Possible Failure of Prosthetic Implants”,IEEE 17thAnnual Conference IEEE Eng. Med. Bio. Soc., 2:1251-1252.
Popovic, M. et al., 2001, “Cloning Biological Synergies Improves Control of the Elbow Neuroprostheses”,IEEE Eng. Med. Bio., 20: 74-81.
Scheiner, A., 1994, “The Effect of Joint Stiffness on Stimulation of the Complete Gait Cycle”,Proc. 16thAnnual Conference of IEEE Eng. Med. Bio. Soc., Engineering Advances: New Opportunities for Biomedical Engineers: 386-387.
Stokes, C.L., et al., 1999, “Asthma PhysioLab: A Dynamic, Computer-Based Mathematical Model of Acute and Chronic Asthma”,Proc. First Joint BMES/EMBS Conf. Serving Humanity, Advancing Technology, Oct. 13-16: 1208.
Yvan, P., et al., 1995, “3D Radiographic Reconstruction of Thoracic Facet Joints”,IEEE 17thAnnual Conference IEEE Eng. Med. Bio. Soc., 1: 397-398.
Defranoux Nadine A.
Dubnicoff Todd B.
Klinke, II David J.
Lewis Annette K.
Paterson Thomas S.
Cooley & Godward LLP
Entelos Inc.
Frejd Russell
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