Method and apparatus for collecting transfusable granulocytes

Surgery – Respiratory method or device – Ozone or ion generation

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128214D, A61M 500

Patent

active

041978471

ABSTRACT:
In carrying out the process of this invention, there is a closed bag system comprising a first bag used for sedimenting the red cells and a second bag used for collecting the sedimented red cells. The two bags are connected by a flexible plastic transfer tube. The sedimenting bag has a second transfer tube leading thereto for introducing the packed red and white cells and the Saline solution of a sedimenting agent. A third tube is connected to the sedimenting bag for withdrawing white cells. The red cell bag has a second tube for the addition of plasma and a third tube for returning the plasma and red cells to a vein of the donor. As an optional feature, the withdrawn whole blood passes directly to an interrupted flow centrifuge which spins off the plasma and platelets, and from which the packed red and white cells are pumped to the sedimenting plastic bag.

REFERENCES:
patent: 3489145 (1970-01-01), Judson et al.
patent: 4058363 (1977-11-01), Silbert
"A Method for Separation of Granulocytes from Normal Human Blood Using Hydroxyethyl Starch", Preparative Biochem, Roy et al., 1971. _
"Increased Efficiency of Leukocyte Collection by the Addition of HES to the Continuous Flow Centrifuge", Blood, Mishler et al., vol. 44, 10-1971. _

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