Method and apparatus for classifying white blood cells

Image analysis – Histogram processing – For setting a threshold

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36441308, 356 39, G06K 900

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048500240

ABSTRACT:
An apparatus for classifying leukocytes comprises a sample image preprocessing unit which modifies the pattern of the nucleus of each of predetermined number of leukocytes extracted from the image of a blood sample, a unit for analyzing each of the processed nucleus patterns and broadly classifying each of the leukocytes into a typical or quasi-typical band form neutrophil, a typical or quasi-typical segmented neutrophil, or other neutrophil in an intermixture domain or a leukocyte other than a neutrophil, and a unit for calculating sample estimation indexes from the numbers of typical and quasi-typical neutrophils and the total number of neutrophils, classifying each of the neutrophils in the intermixture domain into a band form or a segmented neutrophil in accordance with the estimation indexes, and adding the numbers of intermixed band form and segmented neutrophils to the numbers of typical or quasi-typical band form and segmented neutrophils, respectively.

REFERENCES:
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patent: 3832687 (1974-08-01), Miller et al.
patent: 3999047 (1976-12-01), Green
patent: 4045655 (1977-08-01), Suzuki et al.
patent: 4183013 (1980-01-01), Agrawala et al.
patent: 4307376 (1981-12-01), Miller et al.
Bacus et al., "Leukocyte Pattern Recognition", IEEE Transactions on Systems, Man, and Cybernetics, vol. SMC-2, No. 2, Sep. 1972.

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