Method and apparatus for cell sorting

Details Method and apparatus for cell sorting Method and apparatus for cell sorting

2007-01-09

2007-01-09

Wallenhorst, Maureen M. (Department: 1743)

Chemistry: analytical and immunological testing

Biological cellular material tested

C436S150000, C436S164000, C436S172000, C436S177000, C436S180000, C422S068100, C422S073000, C422S082050, C422S082080, C422S082090, C422S105000, C435S029000, C435S287100, C435S287300

Reexamination Certificate

active

10688331

ABSTRACT:
A cell sorter system that includes a precision pump that causes fluid containing cells to enter an inlet port where the fluid is exposed to source light of one or more wavelengths and where cells scatter light or produce fluorescence by known means, and the scattered light and/or fluorescence is used to detect the presence and position of desired cells. The fluid is passed into a select gate that can be magnetostrictive where it is cause to exit one of a plurality of ports, at least one of these ports receiving the desired cells. A controller controls the precision pump, the detection system, and the select gate so that cells are selected from the fluid. An optional vacuum system can be used to pull fluid or cells out of the selected exit port.

REFERENCES:
patent: 3790760 (1974-02-01), Stiller
patent: 3827555 (1974-08-01), Kamentsky et al.
patent: 4158368 (1979-06-01), Clark
patent: 4756427 (1988-07-01), Gohde et al.
patent: 5837200 (1998-11-01), Diessel et al.
patent: 6540895 (2003-04-01), Spence et al.
patent: 6778724 (2004-08-01), Wang et al.
patent: 2003/0027225 (2003-02-01), Wada et al.
Copending U.S. Appl. Nos. 10/690,766, 10/965,287, 10/689,480, 10/965,289.
“A Theoretical and Experimental Study of Magnetostrictive Mini-Actuators” Anjanappa et al, 1994.

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