Method and apparatus for cell analysis

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358107, 382 6, G06F 738, G06K 100

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active

050738577

ABSTRACT:
A pap smear inspection apparatus and method for automated screening of cytological smears for dense, possibly malignant cells includes a specimen slide for receiving a cytological smear and a microscope for enlarging the image of the smear. The microscope is outfitted to receive a video camera for creating an analog video signal corresponding to an area enlarged by the microscope and being observed by the video camea. A video timer synchronizes operation of the smear analysis apparatus. An image window generator focuses the analysis of the apparatus on a sub-area of the entire video image. A converter is provided for converting a digital threshold level into a corresponding analog threshold level. A comparator is used for transforming the analog video input signal into a binary video signal according to the analog threshold levels. A pixel counter sums the number of ON pixels both in the transformed video signal, and within the designated window sub-area of said video signal. A microprocessor compares the digital count output with a user-defined limit on the number of ON pixels allowed to occur within each sub-area under study, and if the limit it exceeded, the current area has failed the test for acceptability.

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