Image analysis – Applications – Biomedical applications
Patent
1996-05-10
1999-03-30
Boudreau, Leo H.
Image analysis
Applications
Biomedical applications
382199, 382266, G06K 900
Patent
active
058898816
ABSTRACT:
A method for detecting malignancy-associated changes. A sample of cells is obtained and stained to identify the nuclear DNA material. The sample is imaged with a digital microscope. Objects of interest are identified in the sample of cells based on the intensity of the pixels that comprise the object versus the average intensity of all pixels in the slide image. An exact edge is located for each object and variations in the illumination intensity of the microscope are compensated for. A computer system calculates feature values for each object and, based on the value of the features, a determination is made whether the cell exhibits malignancy-associated changes or not.
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Garner David M.
Harrison S. Alan
Jaggi Bruno W.
MacAulay Calum E.
Palcic Branko
Bella Matthew C.
Boudreau Leo H.
Oncometrics Imaging Corp.
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