Method and apparatus for automatic competitive binding analysis

Details Method and apparatus for automatic competitive binding analysis Method and apparatus for automatic competitive binding analysis

1978-04-21

1981-04-28

Serwin, Ronald

Chemistry: physical processes

Physical processes

Crystallization

23920, 422 81, 422 82, 204180G, 435291, G01N 3356, G01N 3508

Patent

active

042643279

ABSTRACT:
Automatic continuous competitive binding analyzer comprising: controlled combination and incubation of ligand, labeled ligand, and ligand specific binding agent; isolation of serial samples by spacer fluid; light absorbing agent for identifying portions of stream; light activated fluid control directing fluid flow and processing; separation of bound ligand from unbound ligand; novel electroextraction for separating certain molecules in flowing stream; serially introducing separated portions of stream into label measuring device. Use of a plurality of static detectors to reduce average processing time below radioactivity measurement time when label is radioactive.

REFERENCES:
patent: 3320148 (1967-05-01), Skeggs
patent: 3320149 (1967-05-01), Isreeli
patent: 4009005 (1977-02-01), Johnson
patent: 4128628 (1978-12-01), Brooker
patent: 4141687 (1979-02-01), Forrest et al.
patent: 4153416 (1979-05-01), Bonner et al.

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