Chemistry: analytical and immunological testing – Biological cellular material tested
Patent
1985-08-05
1988-04-26
Richman, Barry S.
Chemistry: analytical and immunological testing
Biological cellular material tested
436 45, 436177, 422 72, 2105121, 210787, 494 16, 494 17, B04B 502, B04B 1100, B01D 2126
Patent
active
047404728
ABSTRACT:
A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises (1) a whole blood sample disc, (2) a serum sample disc, (3) a sample preparation rotor, and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc in capillary tubes filled by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analytical rotor for analysis by conventional methods.
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Burtis et al., "The Development of Rotors Having Separate Sample and Reagent Transfer Channels for Use with Centrifugal Fast Analyzers", Analytical Letters, 7(8&9), 1974.
J. C. Mailen et al., "Techniques for Fabrication and Assembly of Rotors for Use in a Miniature Fast Analyzer", Analytical Letters, 6(3), 1973.
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Burtis Carl A.
Johnson Wayne F.
Walker William A.
Hamel Stephen D.
Hightower Judson R.
Kummert Lynn M.
Richman Barry S.
The United States of America as represented by the United States
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