Method and apparatus for assaying whole blood

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 7, 435810, 435311, 436177, 436825, 422 61, 422102, C12Q 170

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049651870

ABSTRACT:
A method of assaying a sample of whole blood for one member of a specific binding pair, the method involving treating the sample with salt to alter the red blood cells in the sample to decrease their ability to pass through filter media, exposing the resulting sample to a filter which retains the red blood cells but allows the passage therethrough of filtrate of the sample containing the member of the specific binding pair, and measuring the member of the filtrate.

REFERENCES:
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patent: 3825410 (1974-07-01), Bagshawe
patent: 3929583 (1975-08-01), Sharpe
patent: 3972812 (1976-08-01), Gresl, Jr.
patent: 4301010 (1981-11-01), Eddleman et al.
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patent: 4806467 (1989-02-01), Porter et al.
New Brunswick ad, "The Iso-Grid System."
Marchalonis et al., Antibody as a Tool, John Wiley & Sons, 1982, p. 377.
Work et al., Laboratory Techniques in Biochemistry and Molecular Biology, vol. 6, Elsevier Press, 1982, p. 17.

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