Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1994-11-30
1996-03-26
Beisner, William H.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4352932, 4352951, 4352952, 4353021, C12N 500, C12M 300
Patent
active
055019714
ABSTRACT:
A method and apparatus cultivates anchorage and nonanchorage cell in a reactor. A reactor includes a basket type packed bed and an internal recirculation device. The basket includes a top and bottom portion for allowing medium to flow uniformly through the basket. Medium flows downwardly from the top of the basket through the basket for providing gentle flow and preventing removal of cells from the carrier. Preferably, the carrier is formed of a fiber matrix.
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Animal Cells--The Breakthrough to a Dominant Technology, Brian Griffiths Division of Biologics, PHLS CAMR, Cytotechnology 3: 109-116, 1990.
Freedman David
Kadouri Avinoam
Wang Guozheng
Beisner William H.
New Brunswick Scientific Co., Inc.
Woodbridge Richard C.
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