Method and apparatus for analysing nucleic acid sequence

Details Method and apparatus for analysing nucleic acid sequence Method and apparatus for analysing nucleic acid sequence

2005-07-20

2009-11-10

Brusca, John S (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C435S006120

Reexamination Certificate

active

07617054

ABSTRACT:
A method of analyzing nucleic acid sequence data produced by automated sequencer comprises scaling the data according to a map of relative heights of homozygous base data. An apparatus for conducting the method comprises means for scaling the data according to a map of relative heights of homozygous base data.

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Nickerson et al. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing Nucleic Acids Research vol. 25, pp. 2745-2751 (1997).
Ewing et al. Base-calling of Automated Sequencer Traces Using Phred. I. Accuracy Assessment Genome Research vol. 8, pp. 175-185 (1998).
International Search Report dated Aug. 31, 2005 issued in PCT/AU2005/001065.

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