Method and apparatus for aiding in the reduction of incidence of

Details Method and apparatus for aiding in the reduction of incidence of Method and apparatus for aiding in the reduction of incidence of

1988-02-19

1990-05-01

Millin, V.

Tobacco

Antismoking product or device, i.e., deterent

A24F 4700, A61K 900

Patent

active

049209892

ABSTRACT:
A method of aiding in the reduction of incidence of tobacco smoking. The method comprises applying a patch containing nicotine to the skin of a person with whom smoking reduction is desired and allowing the nicotine to transdermally migrate into the person's bloodstream to achieve a desired systemic nicotine level. The method also comprises the simultaneous administration of a nicotine containing aerosol spray to the oral cavity of the user in order to provide the desired sensations in the respiratory tract to which the user is accustomed from normal tobacco smoke. A combination of the spray and transdermal patch is also provided such that an occlusive patch is applied to the skin of the person with whom smoking reduction is desired and the nicotine containing aerosol spray is delivered to the oral cavity simultaneously with the application of the nicotine from the patch.

REFERENCES:
patent: 4473083 (1984-09-01), Maganias
patent: 4579858 (1986-04-01), Ferno et al.
patent: 4597961 (1986-07-01), Etscorn
patent: 4635651 (1987-01-01), Jacobs
Tobacco Alkaloids and Related Compounds edited by Von Euler, pp. 3-13, A Pergamon Press Book, 1965.
"Bronchial Effects of Aerosolized .DELTA.9-Tetrahydroconnobol in Healthy and Asthmatic Subjects" by Tasbin et al., American Review of Respiratory Disease, vol. 115, 1977.
"Drug Permeation through Human Skin: Theory and In Vitro Experimental Measurement" by Chandrasekaran et al., AICHE (vol. 21, No. 5), Sep. 1975, pp. 985-993.

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