Optical: systems and elements – Compound lens system – Microscope
Patent
1995-04-18
1997-09-23
Dzierzynski, Paul M.
Optical: systems and elements
Compound lens system
Microscope
359395, 359393, 359398, 359368, 359369, 250311, G02B 2126, G02B 2100, G02B 2136, G01N 2101
Patent
active
056710860
ABSTRACT:
An apparatus using electrophoresis provides accurate manipulation of an object on a microscope stage for further manipulations add reactions. The present invention also provides an inexpensive and easily accessible means to move an object without damage to the object. A plurality of electrodes are coupled to the stage in an array whereby the electrode array allows for distinct manipulations of the electric field for accurate manipulations of the object. There is an electrode array control coupled to the plurality of electrodes for manipulating the electric field. In an alternative embodiment, a chamber is provided on the stage to hold the object. The plurality of electrodes are positioned in the chamber, and the chamber is filled with fluid. The system can be automated using visual servoing, which manipulates the control parameters, i.e., x, y stage, applying the field, etc., after extracting the significant features directly from image data. Visual servoing includes an imaging device and computer system to determine the location of the object. A second stage having a plurality of tubes positioned on top of the second stage, can be accurately positioned by visual servoing so that one end of one of the plurality of tubes surrounds at least part of the object on the first stage.
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Fish Richard H.
Johnston William E.
Maestre Marcos F.
Parvin Bahram A.
Dzierzynski Paul M.
Martin Paul R.
Sikd-er Mohammad Y.
The Regents University of California
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