Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Reexamination Certificate
2006-10-18
2009-12-15
Haq, Shafiqul (Department: 1641)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
C530S405000, C530S406000, C548S215000
Reexamination Certificate
active
07632928
ABSTRACT:
An antibody and immunogen for generating an antibody to nitrofuran and/or nitrofuran metabolite such as tissue or protein bound nitrofuran metabolites. Nitrofurans and and/or nitrofuran metabolites in a biological sample can be detected by contacting the sample with the antibodies to form a complex that can be detected. The antibodies may also be incorporated into test kits for the detection of nitrofuran and/or nitrofuran metabolites.
REFERENCES:
patent: 3957766 (1976-05-01), Berger et al.
patent: 3994882 (1976-11-01), Hirao et al.
patent: 4500516 (1985-02-01), Grinberg et al.
patent: 4794120 (1988-12-01), Manoury et al.
patent: 5086068 (1992-02-01), Raleigh et al.
patent: 2003/0166645 (2003-09-01), Ala et al.
Bryant, Christopher & Deluca, Marlene, Purfication and Characterization of an Oxygen-insensitive NAD (P) H Nitroreductase from Enterobacter cloacae, The Journal of Biological Chemistry, Mar. 5, 1991, vol. 266, No. 7, pp. 4119-4125, The American Society for Biochemistry and Molecular Biology, Inc. USA.
Enzymatic Assay of Diaphorase, May 17, 1998.
Vroomen, LHM, In vivo and in vitro metabolic studies of furazolidone, Wageningen Dissertation Abstracts, WAU Dissertation No. 1182, Nov. 24, 1987.
R-Biopharm, Ridascreen, Nitrofuran (AMOZ), retrieved from the Web Feb. 9, 2004, www.r-biopharm.com/foodandfeed/ridascreen—nitrofuran—amoz.php, pp. 1-2.
Takino, Masahiko, Determination of the Metabolites of Nitrofuran Antibacterial Drugs in Chicken Tissue by Liquid Chromatograph-Electrospray Ionization-Mass Spectrometry (LC-ESI-MS) Application www.agilent.com/chem, Mar. 19, 2003, pp. 1-9, Agilent Technologies, Inc. USA.
Bryant, D.W., McCalla, D.R., Leeksma, M., & Laneuville, P. Type I nitroreductases ofEscherichia coli, Canadian Journal of Microbiology, vol. 27, pp. 81-86, 1981, Canada.
Ridascreen Nitrofuran (AOZ), Art No. R3701, R-Biopharm AG, Darmstadt, Germany, pp. 1-34, 2002.
Tatsumi, Kiyoshi, Nakabeppu, Hitoshi, Takahashi, Yoshihiro & Kitamura, Shigeyuki, Metabolism in Vivo of Furazolidone: Evidence for Formation of an Open-Chain Carboxylic Acid and @-Ketoglutaric Acid from the Nitrofuran in Rats Archives of Biochemistry and Biophysics, vol. 234, No. 1, pp. 112-116, 1984, Academic Press, Inc.
State Institute for Quality Control of Agricultural Products (RIKILT) Wageningen, & Department of Toxicology of the Agricultural University, TNO-Institute of Animal Nutrition and Physiology The Netherlands, Nov. 1987, pp. 1-158.
Cooper, K.M., Caddell, A., Elliott, C.T., Kennedy, D.Glenn, Analytica Chimica Acta 520 (2004) pp. 79-86, Production and Characterisation of polyclonal antibodies to a derivative of 3-amino-2-oxazolidinone, a metabolite of the nitrofuran furazolidone, United Kingdom, Elsevier B.V.
Newcombe, P.J., & Norris, R.K., Stereolectronic Control of the Rate of Ring Opening in Azidofurans, Tetrahedron Letters, vol. 22, pp. 699-700, Pergamon Press, Ltd, 1981, Great Britain.
Povazanec, F., Kovac, J., & Hesek, D., Collection Czechoslov. Chem. Commun, vol. 45, pp. 150-153, 1980, Czech Republic Opening of the Furan Ring in 5-Azido-2-Furaldehyde.
Hoogenboom, L.A.P., Kammen Van, M. Huveneers-Oorsprong, MBM, Kuiper, H.A., Study on the Role of Glutathione in the Biotransformation and Toxicity of Furazolidone Using Pig Hepatocytes, Toxic. in Vitro, vol. 6, No. 3, pp. 227-237, 1992, Great Britain Pergamon Press, Ltd.
Vass, M., Kotkova, L., Diblikova, I., Nevorankova, Z., Cooper, K.M., Kennedy, D.G., & Franek, M., Production and characterization of monoclonal antibodies for the detection of AOZ, a tissue bound metabolite of furazolidone, pp. 300-310, Czech Republic, 2005.
Diblikova, I., Cooper, K.M., Kennedy, D.G. & Franek, M., Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation, Analytica Chimica Acta(540) 2005, pp. 285-292, Elsevier B.V.
Cooper, K.M., Elliott, C.T., & Kennedy, D.G., Detection of 3-amino-2-oxazolidinone (AOZ), a tissue-bound metabolite of the nitrofuran furazolidone, in prawn tissue by enzyme immunoassay Food Additives and Contaminants, vol. 21, No. 9, pp. 841-848, Taylor & Francis Ltd. 2004 United Kingdom.
Raleigh, J.A., & Koch, C.J., Biochemical Pharmacology, vol. 40 No. 11, pp. 2457-2464, 1990, Pergamon Press, Great Britain Importance of Thiols in the Reductive Binding of 2-Nitroimidazoles to Macromolecules.
Raleigh, J.A., Zeman, E.M., Rathman, M., Ladine, J.K., Cline, J.M., & Thrall, D.E., Development of an Elisa for the Detection of 2-Nitroimidazole Hypoxia Markers Bound to Tumor Tissue, Int. Journal of Radiation Oncology, Biol. Phys. vol. 22, pp. 403-405, 1992, Pergamon Press, USA.
Raleigh, J.A., La Dine, J.K., Cline, J.M. & Thrall, D.E., An Enzyme-linked immunoabsorbent assay for hypoxia marker binding in tumours, Br. J. Cancer, pp. 66-71, 1994, USA.
Thrall, D.E., McEntee, M.C., Cline, J.M., & Raleigh, J.A., Elisa Quantification of CCI-103F Binding in Canine Tumors Prior to and DuringIRadiation, Int. J. Radiation Oncology Biol. Phys. vol. 28, No. 3, pp. 649-659, 1994, Elsevier Science, Ltd. USA.
Joseph, P., Jaiswal, A.K., Stobbe, C.C., & Chapman, J.D., The Role of Specific Reductases in the Intracellular Activatation and Binding of 2-Nitroimidazoles, Int. J. Radiation Oncology Biol. Phys., vol. 29, No. 2, pp. 351-355, 1994, Elsevier Science Ltd USA.
Vroomen, L.H.M., Berghmans, M.C.J., Groten, J.P., Koeman, J.H., Van Bladeren, P.J., Reversible Interaction of a Reactive Intermediate Derived from Furazolidone with Glutathione and Protein, Toxicology and Applied Pharmacology, 95, pp. 53-60, 1988, Academic Press, Inc.
Ebetino, F.F., Carroll, J.J., & Gever, G., Reduction of Nitrofurans I. Aminofurans, May 1962, vol. 5, pp. 513-524.
Beckett, A.H., & Robinson, A.E., The Reactions of Nitrofurans with Bacteria -II. Reduction of a Series of Antibacterial Nitrofurans by Aerobacter aerogenes, Journal of Medicinal and Pharmaceutical Chemistry, vol. 1, No. 2, pp. 135-152, 1959.
Hoogenboom, L.A.P., Kammen, M Van, Berghmans, M.C.J., Koeman, J.H. & Kuiper, H.A., The Use of Pig Hepatocytes to Study the Nature of Protein-Bound Metabolites of Furazolidone: A New Analytical Method for their Detection, Fd Chem. Toxic, vol. 29, No. 5, pp. 321-328, 1991, Pergamon Press.
Kazanis, S. & McClelland, R.A., Electrophilic Intermediate in the Reaction of Glutathione and Nitrosoarenes, American Chemical Society, J. Am. Chem. Soc., vol. 114, No. 8, pp. 3052-3059, 1992.
Silva, J.M., Khan, S., & O'Brien, P.J., Molecular Mechanisms of Nitrofurantoin-Induced Hepatocyte Toxicity in Aerobic versus Hypoxic Conditions, Archives of Biochemistry and Biophysics, vol. 305, No. 2, pp. 362-369, 1993, Academic Press, Inc.
Mattamal, M.B., Zenser, T.V., Palmier, M.O., & Davis, B.B., Renal Reduced Nicotinamide Adenine Dinucleotide Phosphate: cytochrome c Reductase-mediated Metabolism of the Carcinogen N-[4-(5-Nitro-2-furyl )-2-thiazolyl]acetamide, Cancer Research, vol. 45, pp. 149-156, Jan. 1985, USA.
Folker Lieb & Karl Eiter, Nucleophile Substitutionsreaktionen am 5-Nitro-2-furfurol, Liebigs Ann. Chem, vol. 761, pp. 130-136, 1972, Germany.
Miller, C., Folkes, L.K., Mottley, C., Wardman, P. & Mason, R.P., Revisiting the Interaction of the Radical Anion Metabolite of Nitrofurantoin with Glutathione, Archives of Biochemistry and Biophysics, vol. 397, No. 1, Jan. 2002, pp. 113-118, Elsevier Science, Ltd. USA.
Gottschall, D.W., & Wang, R., Depletion and Bioavailability of [14C] Furazolidone Residues in Swine Tissues, J. Agric. Food Chem. vol. 43,9pp. 2520-2525, 1995, USA.
Hoogenboom, L.A.P., Polman, TH.H.G., Lommen, A., Huveneers, M.B.M. & Vanjrhijn, J., Biotransformation of furaltadone by pig hepatocytes andSalmonella typhimuriumTA 100 bacteria, and the formation of Protein-bound metabolites, Xenobiotica, vol. 24, No. 8, pp. 713-727, 1994, Taylor & Francis, Ltd.
Horne, E., Cadogan, A., O'Keeffe, M.O., & Hoogenboom, L.A.P., Analysis of Protein-bound Metabolites of Furazolidone
Charm Stanley E.
Law Say-Jong
Saul Steven J.
Charm Sciences, Inc
Haq Shafiqul
Long Richard J.
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