Method and agent for the therapy of immunocomplex diseases

Details Method and agent for the therapy of immunocomplex diseases Method and agent for the therapy of immunocomplex diseases

1979-12-10

1984-10-30

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

424177, A61K 3900, A61K 3704, A61K 39395

Patent

active

044799349

ABSTRACT:
What is disclosed is a method for the therapy of immunocomplex diseases with an agent which contains Fc-reagents that react with the Fc-part of the antibody contained in the immunocomplex, but which themselves do not posses an immunologically active Fc-part or an Fc-part capable of being activated.

REFERENCES:
Chemical Abstracts, vol. 82, p. 361, Abst. No. 84193u, "Interaction of Antibodies, Complement Components and Various Cell Types in Immunity Against Viruses and Pyogeneic Bacteria", 1975.
Chemical Abstracts, vol. 79, p. 318, Abst. No. 30333j, Eden et al., "Mechanism of Binding Soluble Immune Complexes to Lymphocytes", 1973.
Chemical Abstracts, vol. 79, p. 318, Abst. No. 30334k, Yoshino et al., "Neutralization of Herpes Simplex Virus, VI, Mode of Action of Complement Upon Antibody-Sensitized Virus", 1973.
Chemical Abstracts, vol. 84, p. 260, Abst. No. 56290w, Masson et al., "Analysis of Biological Fluids", 1976.
Chemical Abstracts, vol. 84, p. 260, Abst. No. 56291x, Masson et al., "Analysis of Biological Fluids", 1976.
Nisonoff et al., Arch. Biochem. Biophys., vol. 89, p. 230, (1960).
Sedlacek et al., Behring Institute Mitteilungen, vol. 64, p. 78, (1979).
Sedlacek, Klin. Wochenschr., vol. 58, pp. 543, 593, (1980).
Haakenstad et al., Biology of Immune Complexes in "Autoimmunity", Ed. by Talal, Academic Press, (1977), pp. 278-350.
Porter, Biochem. J., vol. 73, p. 119, (1959).
Haupt et al., Klinische Wochenschryt, vol. 47, p. 270, (1969).
Nisonoff et al., Arch. Biochem. Biophys., vol. 89, p. 230, (1960).

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