Method and a pharmaceutical composition for the inhibition of an

Details Method and a pharmaceutical composition for the inhibition of an Method and a pharmaceutical composition for the inhibition of an

1988-03-25

1992-08-04

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 24, 514 58, 514475, A61K 31715, A61K 3170

Patent

active

051359197

ABSTRACT:
Fumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fumagillin or its salt, and an agent which potentiates angiogenesis inhibition such as heparin and sulfated cyclodextrins such as beta-cyclodextrin tetradecasulfate.

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