Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-04-18
1999-12-14
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 536 237, C12N 112, C12N 1500, C07H 2104, C12P 2106
Patent
active
060016019
ABSTRACT:
The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
REFERENCES:
patent: 5302527 (1994-04-01), Birkett et al.
R. Calendar et al., "Purification and Physical Characterization of Tyrosyl Ribonucleic Acid Synthetases from Escherichia coli and Bacillus subtilis", Biochemistry, 5(5) pp. 1681-1690 (1966).
J. Hughes et al., "How Does Pseudomonas Fluorescens, the Producing Organism of the Antibiotic Pseudomonic Acid A, Avoid Suicide?", FEBS Letters, 122(2) pp. 322-324 (1980).
Menguito et al., "Molecular Cloning, Sequence, Structural Analysis and Expression of the Histidyl-tRNA Synthetase Gene from Streptococcus equisimilis," Nucleic Acids Research, 21(3) pp. 615-620 (1993).
Von Der Haar et al., "Target Directed Drug Synthesis: The Aminoacyl-tRNA Synthetases as Possible Targets," Angewandte Chemie, 20(3) pp. 217-223 (1981).
Meinnel et al., "Aminoacyl-tRNA Synthetases: Occurrence, Structure, and Function," In: tRNA: Structure, Biosynthesis, and Function, American Society for Microbiology, pp. 251-292 (1995).
Alonso, et al., Molecular Cloning, Genetic Characterization and DNA Sequence Analysis of the recM Region of Bacillus subtilis. Nucleic Acids Research, Dec. 1990, vol. 18, No. 23, pp. 6771-6777.
Mechulam, et al., Methionyl-tRNA Synthetase from Bacillus stearothermophilus: Structural and Functional Identities with the Escherichia coli Enzyme. Nucleic Acids Research. Jul. 1991, vol. 19, No. 13, pp. 3673-3681.
Nureki, et al., Methionyl-tRNA Synthetase Gene From an Extreme Thermophile, Thermus thermophilus HB8. The Journal of Biological Chemistry. Feb. 15, 1991, vol. 266, No. 5, pp. 3268-3277.
Mindich et al (Journal of Virology vol. 62, No. 4, Apr. 1988 pp. 1180-1185).
Lazar et al (Molecular & Cellular Biology vol. 8 No. 3, Mar. 1988 pp. 1247-1252).
Burgess et al (J. of Cell Biology vol. 111, Nov. 1990, pp. 2129-2138).
Sallgaller et al (Cancer Immunol. Immunother. vol. 39, 1990 pp. 105-116).
Lindler et al (J. of Bacteriology vol. 169, No. 7, Jul. 1987 pp. 3199-3208) .
Caputa Anthony C.
Deibert Thomas S.
Gimmi Edward R.
King William T.
Navarro Mark
LandOfFree
Methionyl tRNA synthetase polynucleotides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methionyl tRNA synthetase polynucleotides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methionyl tRNA synthetase polynucleotides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-862156