Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-04-03
2007-04-03
Tsang, Cecilia J. (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S300000, C530S329000, C530S344000, C514S002600, C514S014800, C514S015800
Reexamination Certificate
active
10741831
ABSTRACT:
A means and method for treating bacterial infection, providing antioxidant activity, and chelating copper using a copper binding compound produced by methanotrophic bacteria is described. The compound, known as methanobactin, is the first of a new class of antibiotics having gram-positive activity. Methanobactin has been sequenced, and its structural formula determined.
REFERENCES:
HJ Kim, et al. Science (2004), 305 (Sep. 10). 1612-1615.
CM Tellez, et al. Isolation of Copper Biochelates . . . (1998) Appl. Environ. Micobiol. 64(3). 1115-1122.
TK Wood. Active expression of soluble . . . (2002) Microbiology. 148(Nov. 2002). 3328-3329.
JC Murrell. Expression of soluble . . . (2002) Microbiology. 148(Nov. 2002). 3329-3330.
J-Y Xin, et al. Particulate methane . . . (2002) Biochem. Biophys. Res. Comm. 295. 182-186.
HJ Kim, et al. Effects of oxygen . . . (2001) FEMS Micobiol. Letters. 201. 133-138.
A. Gosslau and L. Rensing. Z. Gerentol. Gerlat. (2002) 35, pp. 139-150.
H.J. Kim, et al. Chemtracts- Inorganic Chemistry (2005) 18, pp. 87-92.
Alan A. DiSpirito, et al., Copper-Binding Compounds fromMethylosinus trichosporiumOB3b, Journal of Bicteriology, Jul. 1998, p. 3606-3613.
H de Groot, et al. “Tissue injury by reactive oxygen species and the protective effects of flavonoids”Fundam Clin Pharmacol1998; 12:249-55, XP-001027003.
Zahn et al., “Membrane-Associated Methane Monooxygenase fromMethylococcus capsulatus(Bath)”, Journal of Bacteriology, vol. 178, No. 4, Feb. 1996, p. 1018-1029.
Alterman Michail
DiSpirito Alan A.
Graham David W.
Kim Hyung J.
Larive Cynthia
Iowa State University & Research Foundation, Inc.
Kosar Andrew D.
McKee Voorhees & Sease, P.L.C.
The University of Kansas
Tsang Cecilia J.
LandOfFree
Methanobactin: a copper binding compound having antibiotic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methanobactin: a copper binding compound having antibiotic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methanobactin: a copper binding compound having antibiotic... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3767789