Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1993-04-14
1994-09-06
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514103, 514964, 424419, 424462, 424465, 424468, 424490, 424502, A61K 3166, A61K 950, A61K 916
Patent
active
053448251
ABSTRACT:
The invention relates to a novel advantageous oral dosage form for methanediphosphonates, especially the active ingredient disodium pamidronate. A preferred dosage form comprises:
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Reitsma et al "Apposition and Resorption of Bone During Oral Treatment with (3-Amino-1-Hydroxypropylidine)-1, 1-Bisphosphonate (A, Calcif Tissue Int. (1983) 35:357-361.".
H I J Harinck. et al "Paget's Disease of Bone: Early and Late Responses to Three Different Modes of Treatment With Aminohydroxypropylide Bishosphonate (APD)". British Medical Journal vol. 2 Nov. 21, 1987: 1301-1305.
Green Jonathan
Khanna Satish C.
Ciba-Geigy Corp.
Cintins Marianne M.
Criares T. J.
Fishman Irving M.
Kaiser Karen G.
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